An internal standard for the quantification of SAH
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Unlabeled Version(s)
13603S-Adenosylhomocysteine
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S-Adenosylhomocysteine-d4

Item No. 9000372

Technical Information
Formal Name
S-(5’-deoxyadenosin-5’-yl)-L-homocysteine-d4
Synonyms
  • SAH-d4
Molecular Formula
C14H16D4N6O5S
Formula Weight
Purity
≥99% deuterated forms (d1-d4)
A crystalline solid
DMF: 1 mg/mlDMSO: 5 mg/mlPBS (pH 7.2): 5 mg/ml
SMILES
NC1=NC=NC2=C1N=CN2[C@H]3[C@H](O)[C@H](O)[C@@H](CSC([2H])([2H])C([2H])([2H])[C@H](N)C(O)=O)O3
InChi Code
InChI=1S/C14H20N6O5S/c15-6(14(23)24)1-2-26-3-7-9(21)10(22)13(25-7)20-5-19-8-11(16)17-4-18-12(8)20/h4-7,9-10,13,21-22H,1-3,15H2,(H,23,24)(H2,16,17,18)/t6?,7-,9-,10-,13-/m1/s1/i1D2,2D2
InChi Key
ZJUKTBDSGOFHSH-NMDOHOJQSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    Product Description

    S-Adenosylhomocysteine-d4 (SAH-d4) is intended for use as an internal standard for the quantification of SAH by GC- or LC-MS. S-Adenosyl-L-homocysteine (SAH) is an amino acid derivative and an intermediate, by-product, or modulator of several metabolic pathways, including the activated methyl cycle and cysteine biosynthesis. It is also a product of S-adenosyl-methionine (SAM)-dependent methylation of biological molecules, including DNA, RNA, and histones and other proteins. SAH is a risk factor for many diseases, including cancer and neurodegenerative diseases. In addition, inhibitors that block its hydrolysis are being developed as anti-viral, anti-parasitic, anti-arthritic and immunosuppressive agents.

    WARNING This product is not for human or veterinary use.