An internal standard for the quantification of docosahexaenoic acid ethyl ester
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Unlabeled Version(s)
9090310Docosahexaenoic Acid ethyl ester
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Docosahexaenoic Acid ethyl ester-d5

Item No. 9001245

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoic acid, ethyl ester-d5
CAS Number
2692624-15-8
Synonyms
  • DHA ethyl ester-d5
  • Cervonic Acid ethyl ester-d5
  • 4,7,10,13,16,19-Docosahexaenoic Acid ethyl ester-d5
  • C22:6 n-3 ethyl ester-d5
  • C22:6(4Z,7Z,10Z,13Z,16Z,19Z) ethyl ester-d5
  • SFE 24:6-d5
Molecular Formula
C24H31D5O2
Formula Weight
361.6
Purity
≥99% deuterated forms (d1-d5)
Formulation
A 1 mg/ml solution in ethanol
Solubility(Learn about Variance in Solubility)
DMF: 100 mg/mlDMSO: 100 mg/mlEthanol: 500 mg/mlPBS (pH 7.2): 0.15 mg/ml
SMILES
CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCC(OC([2H])([2H])C([2H])([2H])[2H])=O
InChi Code
InChI=1S/C24H36O2/c1-3-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24(25)26-4-2/h5-6,8-9,11-12,14-15,17-18,20-21H,3-4,7,10,13,16,19,22-23H2,1-2H3/b6-5-,9-8-,12-11-,15-14-,18-17-,21-20-/i2D3,4D2
InChi Key
ITNKVODZACVXDS-HOUNFZJWSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    50 µg

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    100 µg

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    500 µg

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    1 mg

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    Product Description

    Docosahexaenoic acid ethyl ester-d5 (DHA ethyl ester-d5) is intended for use as an internal standard for the quantification of docosahexaenoic acid ethyl ester (Item No. 9090310) by GC- or LC-MS. DHA ethyl ester is an esterified form of the ω-3 fatty acid DHA (Item Nos. 90310 | 17950). DHA ethyl ester increases plasma and erythrocyte membrane DHA levels in rats without altering the content of the ω-6 fatty acid arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607) when administered in the diet at a dose equivalent to 8 mg/kg of DHA.1 DHA ethyl ester (300 mg/kg per day) reduces the number of reference memory errors in an eight-arm radial maze in 100-week old rats.2 Formulations containing DHA ethyl ester, in combination with EPA ethyl ester, have been used as adjuncts in the treatment of hypertriglyceridemia.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Valenzuela, A., Valenzuela, V., Sanhueza, J., et al. Effects of supplementation with docosahexaenoic acid ethyl ester and sn-2 docosahexaenyl monoacylglyceride on plasma and erythrocyte fatty acids in rats. Ann. Nutr. Metab. 49(1), 49-53 (2005).

    2. Gamoh, S., Hashimoto, M., Hossain, S., et al. Chronic administration of docosahexaenoic acid improves the performance of radial arm maze task in aged rats. Clin. Exp. Pharmacol. Physiol. 28(4), 266-270 (2001).