An internal standard for the quantification of palmitic acid
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Palmitic Acid-d2

Item No. 9001876

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
hexadecanoic-2,2'-d2 acid
CAS Number
62689-96-7
Synonyms
  • C16:0-d2
  • Cetylic Acid-d2
  • FA 16:0-d2
  • Hexadecanoic Acid-d2
Molecular Formula
C16H30D2O2
Formula Weight
258.4
Purity
≥98% deuterated forms (d1-d2)
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 20 mg/mlDMSO: 20 mg/mlEthanol: 30 mg/mlEthanol:PBS (pH 7.2) (1:2): 0.25 mg/ml
SMILES
OC(C([2H])([2H])CCCCCCCCCCCCCC)=O
InChi Code
InChI=1S/C16H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16(17)18/h2-15H2,1H3,(H,17,18)/i15D2
InChi Key
IPCSVZSSVZVIGE-DOBBINOXSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    250 mg

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    500 mg

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    1 g

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    Product Description

    Palmitic acid-d2 is intended for use as an internal standard for the quantification of palmitic acid (Item No. 10006627) by GC- or LC-MS. Palmitic acid is a common 16-carbon saturated fat that represents 10-20% of human dietary fat intake and comprises approximately 25 and 65% of human total plasma lipids and saturated fatty acids, respectively.1,2 Acylation of palmitic acid to proteins facilitates anchoring of membrane-bound proteins to the lipid bilayer and trafficking of intracellular proteins, promotes protein-vesicle interactions, and regulates various G protein-coupled receptor functions.1 Red blood cell palmitic acid levels are increased in patients with metabolic syndrome compared to patients without metabolic syndrome and are also increased in the plasma of patients with type 2 diabetes compared to individuals without diabetes.3,4

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Fatima, S., Hu, X., Gong, R.-H., et al. Palmitic acid is an intracellular signaling molecule involved in disease development. Cell. Mol. Life Sci. 76(13), 2547-2557 (2019).

    2. Santos, M.J., López-Jurado, M., Llopis, J., et al. Influence of dietary supplementation with fish oil on plasma fatty acid composition in coronary heart disease patients. Ann. Nutr. Metab. 39(1), 52-62 (1995).

    3. Yi, L.-Z., He, J., Liang, Y.-Z., et al. Plasma fatty acid metabolic profiling and biomarkers of type 2 diabetes mellitus based on GC/MS and PLS-LDA. FEBS Lett. 580(30), 6837-6845 (2006).

    4. Kabagambe, E.K., Tsai, M.Y., Hopkins, P.N., et al. Erythrocyte fatty acid composition and the metabolic syndrome: A National Heart, Lung, and Blood Institute GOLDN study. Clin. Chem. 54(1), 154-162 (2008).