A derivative of S1P
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Sphingosine-1-phosphate (d16:1)

Item No. 9002921

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2S-amino-1-(dihydrogen phosphate), 4E-hexadecene-1,3R-diol
CAS Number
709026-60-8
Synonyms
  • C16 S1P
  • C16 Sphingosine-1-phosphate
  • S1P (d16:1)
Molecular Formula
C16H34NO5P
Formula Weight
351.4
Purity
≥95%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
0.3 M NaOH: 4 mg/mlDMF: <50 µg/mlDMSO: <50 µg/mlPBS (pH 7.2): <50 µg/ml
SMILES
CCCCCCCCCCC/C=C/[C@@H](O)[C@@H](N)COP(O)(O)=O
InChi Code
InChI=1S/C16H34NO5P/c1-2-3-4-5-6-7-8-9-10-11-12-13-16(18)15(17)14-22-23(19,20)21/h12-13,15-16,18H,2-11,14,17H2,1H3,(H2,19,20,21)/b13-12+/t15-,16+/m0/s1
InChi Key
IQHNJQKWEMCXAD-YYZTVXDQSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    500 µg

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    Cayman Chemical
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    Product Description

    C16 Sphingosine-1-phosphate (C16 S1P) is a derivative of sphingosine-1-phosphate (S1P; Item No. 62570) that binds to S1P1/EDG-1, S1P3/EDG-3, and S1P2/EDG-5 receptors with affinities of 115%, 83%, and 103%, respectively, relative to S1P in CHO cells.1 C16 S1P was increased in postmortem primary open angle glaucoma trabecular meshwork samples.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Lim, H.S., Park, J.J., Ko, K., et al. Syntheses of sphingosine-1-phosphate analogues and their interaction with EDG/S1P receptors. Bioor. Med. Chem. Lett. 14(10), 2499-2503 (2004).

    2. Aljohani, A.J., Edwars, G., Guerra, Y., et al. Human trabecular meshwork sphingolipid and ceramide profiles and potential latent fungal commensalism. Invest. Opthalmol. Vis. Sci. 55(6), 3413-3422 (2014).