An internal standard for the quantification of heptadecanoyl-L-carnitine
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Heptadecanoyl-L-carnitine-d3 (chloride)

Item No. 9003263

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(R)-3-carboxy-2-(heptadecanoyloxy)-N,N-dimethyl-N-(methyl-d3)propan-1-aminium, monochloride
Synonyms
  • CAR 17:0-d3
  • C17:0 Carnitine-d3
  • L-Carnitine heptadecanoyl ester-d3
  • L-Heptadecanoylcarnitine-d3
Molecular Formula
C24H45D3NO4 • Cl
Formula Weight
453.1
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 20 mg/mlDMSO: 14 mg/mlEthanol: 10 mg/ml
SMILES
C[N+](C([2H])([2H])[2H])(C)C[C@@H](CC(O)=O)OC(CCCCCCCCCCCCCCCC)=O.[Cl-]
InChi Code
InChI=1S/C24H47NO4.ClH/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-24(28)29-22(20-23(26)27)21-25(2,3)4;/h22H,5-21H2,1-4H3;1H/t22-;/m1./s1/i2D3;
InChi Key
SYUSIANKHPXISE-SZCCLSIUSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    1 mg

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    Product Description

    Heptadecanoyl-L-carnitine-d3 is intended for use as an internal standard for the quantification of heptadecanoyl-L-carnitine by GC- or LC-MS. Heptadecanoyl-L-carnitine is a long-chain acylcarnitine composed of heptadecanoic acid (Item No. 19722) and L-carnitine (Item No. 21489). Levels of heptadecanoyl-L-carnitine are increased in dried blood spots from neonates with propionic or methylmalonic acidemias, inborn errors of metabolism characterized by a deficiency in the activity of propionyl-CoA carboxylase or L-methylmalonyl-CoA mutase or its cofactor 5-deoxyadenosylcobalamin, respectively.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Malvagia, S., Haynes, C.A., Grisotto, L., et al. Heptadecanoylcarnitine (C17) a novel candidate biomarker for propionic and methylmalonic acidemias during expanded newborn screening. Clin. Chim. Acta 450, 342-348 (2015).