An Analytical Reference Material
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  • This product is qualified as a Reference Material that has been manufactured and tested to meet ISO/IEC 17025 and ISO 17034 international standards
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STS-135

Item No. ISO00058

Synonyms
Synonyms
  • 5-fluoro APICA
  • N-adamantyl-1-fluoropentylindole-3-Carboxamide
Technical Information
Formal Name
1-(5-fluoropentyl)-N-tricyclo[3.3.1.13,7]dec-1-yl-1H-indole-3-carboxamide
CAS Number
1354631-26-7
Molecular Formula
C24H31FN2O
Formula Weight
Purity
≥98%
A neat solid
SMILES
FCCCCCN1C=C(C(NC2(C[C@@H]3C4)C[C@H](C3)C[C@H]4C2)=O)C5=CC=CC=C51
InChi Code
InChI=1S/C24H31FN2O/c25-8-4-1-5-9-27-16-21(20-6-2-3-7-22(20)27)23(28)26-24-13-17-10-18(14-24)12-19(11-17)15-24/h2-3,6-7,16-19H,1,4-5,8-15H2,(H,26,28)/t17-,18+,19-,24?
InChi Key
COYHGVCHRRXECF-YGMNDUCWSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    STS-135 is a designer drug purported to be found in herbal blends. This compound features the fluoropentylindole structure of AM2201 (Item No. 10707), a synthetic cannabinoid (CB), as well as an adamantyl carboxamide group, which may increase affinity for the peripheral CB2 receptor.12 The physiological and toxicological properties of STS-135 are not known. This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Makriyannis, A., and Deng, H. Cannabimimetic indole derivatives. US7241799B2, (2001).

    2. Pasquini, S., De Rosa, M., Pedani, V., et al. Investigations on the 4-quinolone-3-carboxylic acid motif. 4. Identification of new potent and selective ligands for the cannabinoid type 2 receptor with diverse substitution patterns and antihyperalgesic effects in mice. J. Med. Chem. 54(15), 5444-5453 (2011).