Dysregulation of the cyclic GMP-AMP (cGAMP) synthase (cGAS) pathway leads to chronic inflammation, autoimmune disorders, and even tumorigenesis; therefore, cGAS modulators are of particular interest in searching for novel ways to treat these diseases. Learn more about Cayman's novel cGAS Inhibitor Screening Assay Kit that directly measures the product of the cGAS reaction, cGAMP. 

Read our article Targeting cGAS Activity in the STING Pathway: Assays for Drug Discovery or watch the Development and Validation of a Novel cGAS Inhibitor Screening Assay virtual scientific poster.