A carotenoid with diverse biological activities
Related Products
Isomer(s)
10010811Lutein
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

Zeaxanthin

Item No. 10009992

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
β,β-carotene-3R,3'R-diol
CAS Number
144-68-3
Synonyms
  • Anchovyxanthin
  • Xanthophyll 3
  • Zeaxanthol
Molecular Formula
C40H56O2
Formula Weight
568.9
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: SolubleDMSO: SolubleEthanol: Soluble
λmax
275, 452, 479 nm
SMILES
O[C@H]1CC(C)(C)C(/C=C/C(C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C2=C(C)C[C@@H](O)CC2(C)C)=C(C)C1
InChi Code
InChI=1S/C40H56O2/c1-29(17-13-19-31(3)21-23-37-33(5)25-35(41)27-39(37,7)8)15-11-12-16-30(2)18-14-20-32(4)22-24-38-34(6)26-36(42)28-40(38,9)10/h11-24,35-36,41-42H,25-28H2,1-10H3/b12-11+,17-13+,18-14+,23-21+,24-22+,29-15+,30-16+,31-19+,32-20+/t35-,36-/
InChi Key
JKQXZKUSFCKOGQ-QAYBQHTQSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    500 µg

    $164

    Add

    1 mg

    $312

    Add
    Lipid Resource Center
    Discover Products & Resources for Lipid Research
    • High-purity lipid standards
    • Lipid roles in biology
    • Lipids in health & disease
    • Lipids for pharmaceutical development
    • Protocols, advice, & resources
    EXPLORE NOW
    Product Description

    Zeaxanthin is a dietary carotenoid that has been found in orange and yellow fruits and has diverse biological activities.1,2,3,4,5 In vivo, zeaxanthin (50 mg/kg) decreases immobility time in the forced swim test and reduces hippocampal levels of IL-6, IL-1β, and TNF-α in a rat model of diabetes induced by streptozotocin (STZ; Item No. 13104).1 It also reduces albuminuria, serum levels of urea nitrogen and malondialdehyde (MDA), and kidney damage in a rat model of STZ-induced diabetic nephropathy.2 It forms the macular pigment in human eyes, and high dietary intake of zeaxanthin is positively correlated with reduced risk of advanced neovascular age-related macular degeneration in humans.3,4,5

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Zhou, X., Gan, T., Fang, G., et al. Zeaxanthin improved diabetes-induced anxiety and depression through inhibiting inflammation in hippocampus. Metab. Brain Dis. 33(3), 705-711 (2018).

    2. Kou, L., Du, M., Zhang, C., et al. The hypoglycemic, hypolipidemic, and anti-diabetic nephritic activities of zeaxanthin in diet-streptozotocin-induced diabetic sprague dawley rats. Appl. Biochem. Biotechnol. 182(3), 944-955 (2017).

    3. Jia, Y.-P., Sun, L., Yu, H.-S., et al. The pharmacological effects of lutein and zeaxanthin on visual disorders and cognition diseases. Molecules 22(4), 610 (2017).

    4. SanGiovanni, J.P., Chew, E.Y., Clemons, T.E., et al. The relationship of dietary carotenoid and vitamin A, E, and C intake with age related macular degeneration in a case-control study. Arch. Ophthalmol. 125(9), 1225-1232 (2007).

    5. Hammond, B.R., Jr. Possible role for dietary lutein and zeaxanthin in visual development. Nutr. Rev. 66(12), 695-702 (2008).