A stable analog of Δ9-THC
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CB-25

Item No. 10010116

Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-cyclopropyl-11-(3-hydroxy-5-pentylphenoxy)-undecanamide
CAS Number
869376-63-6
Molecular Formula
C25H41NO3
Formula Weight
403.6
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 30 mg/mlEthanol: 50 mg/mlEthanol:PBS (pH 7.2) (1:2): 0.3 mg/ml
SMILES
CCCCCc1cc(OCCCCCCCCCCC(=O)NC2CC2)cc(O)c1
InChi Code
InChI=1S/C25H41NO3/c1-2-3-10-13-21-18-23(27)20-24(19-21)29-17-12-9-7-5-4-6-8-11-14-25(28)26-22-15-16-22/h18-20,22,27H,2-17H2,1H3,(H,26,28)
InChi Key
XFHZHCKWTBGPFD-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $36

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    5 mg

    $132

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    10 mg

    $253

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    Product Description

    CB-25 is a stable analog of Δ9-tetrahydrocannabinol (THC) and anandamide (AEA). It exhibits high affinity for the central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors with Ki values of 5.2 and 13 nM, respectively. CB-25 behaves as an inverse agonist for the CB1 receptor as assessed in a cyclic AMP (cAMP) functional assay.1,2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Brizzi, A., Brizzi, V., Cascio, M.G., et al. Design, synthesis, and binding studies of new potent ligands of cannabinoid receptors. J. Med. Chem. 48(23), 7343-7350 (2005).

    2. Cascio, M.G., Bisogno, T., Palazzo, E., et al. In vitro and in vivo pharmacology of synthetic olivetol- or resorcinol-derived cannabinoid receptor ligands. Br. J. Pharmacol. 149(4), 431-440 (2006).