An internal standard for the quantification of (S)-(+)-clopidogrel
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Unlabeled Version(s)
21002(S)-(+)-Clopidogrel (sulfate)
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(S)-(+)-Clopidogrel-d3 (sulfate)

Item No. 10010673

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(αS)-α-(2-chlorophenyl)-6,7-dihydro-thieno[3,2-c]pyridine-5(4H)-acetic acid, methyl-d3 ester, monosulfate
CAS Number
1217643-68-9
Molecular Formula
C16H13ClD3NO2S • H2SO4
Formula Weight
422.9
Purity
≥99% deuterated forms (d1-d3)
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 10 mg/mlDMF:PBS (pH 7.2) (1:4): 0.2 mg/mlDMSO: 10 mg/mlEthanol: 3 mg/ml
SMILES
ClC(C=CC=C1)=C1[C@@H](C(OC([2H])([2H])[2H])=O)N2CCC3=C(C=CS3)C2.OS(=O)(O)=O
InChi Code
InChI=1S/C16H16ClNO2S.H2O4S/c1-20-16(19)15(12-4-2-3-5-13(12)17)18-8-6-14-11(10-18)7-9-21-14;1-5(2,3)4/h2-5,7,9,15H,6,8,10H2,1H3;(H2,1,2,3,4)/t15-;/m0./s1/i1D3;
InChi Key
FDEODCTUSIWGLK-CZXUMKGOSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    1 mg

    $90

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    5 mg

    $392

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    10 mg

    $696

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    Product Description

    (S)-(+)-Clopidogrel-d3 is intended for use as an internal standard for the quantification of (S)-(+)-clopidogrel (Item No. 21002) by GC- or LC-MS. (S)-(+)-Clopidogrel is a prodrug form of the active metabolite of clopidogrel, which is a purinergic P2Y12 receptor antagonist.1 It inhibits aggregation of rat platelets induced by ADP, collagen, or thrombin ex vivo (ID50s = 4, 4.8, and 2.9 mg/kg, respectively). (S)-(+)-Clopidogrel increases tail bleeding time in rats in a dose-dependent manner. Formulations containing (S)-(+)-clopidogrel have been used in the treatment of acute coronary syndrome and peripheral artery disease and to reduce the reoccurrence of myocardial infarction and stroke.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Herbert, J., Frehel, D., Vallée, E., et al. Clopidogrel, a novel antiplatelet and antithrombotic agent. Cardiovasc. Drug Rev. 11(2), 180-198 (1993).