A prodrug form of the active metabolite of clopidogrel
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(S)-(+)-Clopidogrel (sulfate)

Item No. 21002

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
S-α-(2-chlorophenyl)-6,7-dihydro-thieno[3,2-c]pyridine-5(4H)-acetic acid, methyl ester, monosulfate
CAS Number
120202-66-6
Synonyms
  • SR 25990C
Molecular Formula
C16H16ClNO2S • H2SO4
Formula Weight
419.9
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 10 mg/mlDMF:PBS (pH 7.2) (1:4): 0.2 mg/mlDMSO: 10 mg/mlEthanol: 3 mg/ml
SMILES
ClC1=CC=CC=C1[C@@H](C(OC)=O)N2CCC(SC=C3)=C3C2.O=S(O)(O)=O
InChi Code
InChI=1S/C16H16ClNO2S.H2O4S/c1-20-16(19)15(12-4-2-3-5-13(12)17)18-8-6-14-11(10-18)7-9-21-14;1-5(2,3)4/h2-5,7,9,15H,6,8,10H2,1H3;(H2,1,2,3,4)/t15-;/m0./s1
InChi Key
FDEODCTUSIWGLK-RSAXXLAASA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    25 mg

    $36

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    50 mg

    $68

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    100 mg

    $123

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    250 mg

    $268

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    Product Description

    (S)-(+)-Clopidogrel is a prodrug form of the active metabolite of clopidogrel, which is a purinergic P2Y12 receptor antagonist.1 It inhibits aggregation of rat platelets induced by ADP, collagen, and thrombin ex vivo (ID50s = 4, 4.8, and 2.9 mg/kg). (S)-(+)-Clopidogrel increases tail bleeding time in rats in a dose-dependent manner. Formulations containing (S)-(+)-clopidogrel have been used in the treatment of acute coronary syndrome and peripheral artery disease and to reduce the reoccurrence of myocardial infarction and stroke.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Herbert, J., Frehel, D., Vallée, E., et al. Clopidogrel, a novel antiplatelet and antithrombotic agent. Cardiovasc. Drug Rev. 11(2), 180-198 (1993).