A selective MBT inhibitor
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UNC669

Item No. 10875

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(5-bromo-3-pyridinyl)[4-(1-pyrrolidinyl)-1-piperidinyl]-methanone
CAS Number
1314241-44-5
Molecular Formula
C15H20BrN3O
Formula Weight
338.2
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 20 mg/mlDMF:PBS(pH 7.2)(1:1): 0.5 mg/mlDMSO: 0.5 mg/mlEthanol: 10 mg/ml
λmax
204, 274 nm
SMILES
BrC1=CN=CC(C(N2CCC(N3CCCC3)CC2)=O)=C1
InChi Code
InChI=1S/C15H20BrN3O/c16-13-9-12(10-17-11-13)15(20)19-7-3-14(4-8-19)18-5-1-2-6-18/h9-11,14H,1-8H2
InChi Key
CQERVFFAOOUFEQ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    5 mg

    $41

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    10 mg

    $75

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    25 mg

    $128

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    50 mg

    $178

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    Product Description

    UNC669 is an inhibitor of the MBT domain of L3MBTL1 with an IC50 value of 6 µM.1 It is 5- and 10-fold selective for L3MBTL1 over the related proteins L3MBTL3 and L3MBTL4.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Herold, J.M., Wigle, T.J., Norris, J.L., et al. Small-molecule ligands of methyl-lysine binding proteins. J. Med. Chem. 54, 2504-2511 (2011).