A mycotoxin
Related Products
Isomer(s)
20437Aflatoxin R0
Labeled Version(s)
31261Aflatoxin B2-13C17
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Product Categories

Product Type

Environmental Toxicology
Toxins
Mycotoxins

Aflatoxin B2

Item No. 11294

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2,3,6aR,8,9,9aS-hexahydro-4-methoxy-cyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione
CAS Number
7220-81-7
Synonyms
  • AFB2
  • Dihydroaflatoxin B1
Molecular Formula
C17H14O6
Formula Weight
314.3
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 20 mg/mlDMF:PBS(pH 7.2)(1:1): 0.5 mg/mlDMSO: 12 mg/ml
λmax
202, 220, 265, 363 nm
SMILES
O=C1C2=C(CCC2=O)C3=C(C([C@](CCO4)([H])[C@]4([H])O5)=C5C=C3OC)O1
InChi Code
InChI=1S/C17H14O6/c1-20-10-6-11-14(8-4-5-21-17(8)22-11)15-13(10)7-2-3-9(18)12(7)16(19)23-15/h6,8,17H,2-5H2,1H3/t8-,17+/m1/s1
InChi Key
WWSYXEZEXMQWHT-RBHXEPJQSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Aflatoxin B2 (AFB2) is a mycotoxin that has been found in A. terricola.1 It induces hepatic autophagy and apoptosis in broiler chickens when administered at doses of 0.2, 0.4, and 0.8 mg/kg.2 AFB2 (0.5 and 1 mg/animal) also induces parenchymal cell hyperplasia in rats.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Moubasher, A.H., el-Kady, I.A., and Shoriet, A. Toxigenic Aspergilli isolated from different sources in Egypt. Ann. Nutr. Aliment. 31(4-6), 607-615 (1977).

    2. Chen, B., Li, D., Li, M., et al. Induction of mitochondria-mediated apoptosis and PI3K/Akt/mTOR-mediated autophagy by aflatoxin B2 in hepatocytes of broilers. Oncotarget 7(51), 84989-84998 (2016).

    3. Wogan, G.N., Edwards, G.S., and Newberne, P.M. Structure-activity relationships in toxicity and carcinogenicity of aflatoxins and analogs. Cancer Res. 31(12), 1936-1942 (1971).