A mutagenic metabolite of aflatoxin B1
Related Products
Isomer(s)
11294Aflatoxin B2
Parent Compound(s)
11293Aflatoxin B1
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Aflatoxin R0

Item No. 20437

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2,3,6aR,9aS-tetrahydro-1S-hydroxy-4-methoxy-cyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-11(1H)-one
CAS Number
29611-03-8
Synonyms
  • Aflatoxicol
Molecular Formula
C17H14O6
Formula Weight
314.3
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Methanol: 1 mg/ml
SMILES
O=C1C2=C(CC[C@@H]2O)C3=C(C([C@@](C=CO4)([H])[C@@]4([H])O5)=C5C=C3OC)O1
InChi Code
InChI=1S/C17H14O6/c1-20-10-6-11-14(8-4-5-21-17(8)22-11)15-13(10)7-2-3-9(18)12(7)16(19)23-15/h4-6,8-9,17-18H,2-3H2,1H3/t8-,9-,17+/m0/s1
InChi Key
WYIWLDSPNDMZIT-IRWWLHRVSA-N
Origin
Fungus/Aspergillus flavus
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $601

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    Product Description

    Aflatoxin R0 is a metabolite of the carcinogenic mycotoxin aflatoxin B1 (Item No. 11293).1 Aflatoxin R0 is produced by metabolism in animals as well as in fungi and can be reverted to the parent compound in fungi.1,2 Aflatoxin R0 is highly mutagenic when tested in the Ames' in vitro microbial detection system for carcinogens.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Nakazato, M., Morozumi, S., Saito, K., et al. Interconversion of aflatoxin B1 and aflatoxicol by several fungi. Appl. Environ. Microbiol. 56(5), 1465-1470 (1990).

    2. Wong, J.J., and Hsieh, D.P. Mutagenicity of aflatoxins related to their metabolism and carcinogenic potential. Proc. Natl. Acad. Sci. USA 73(7), 2241-2244 (1976).