A mycotoxin
Related Products
Isomer(s)
11297Aflatoxin M1
Labeled Version(s)
31262Aflatoxin G1-13C17
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Aflatoxin G1

Item No. 11295

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(7aR,10aS)-3,4,7a,10a-tetrahydro-5-methoxy-1H,12H-furo[3',2':4,5]furo[2,3-h]pyrano[3,4-c][1]benzopyran-1,12-dione
CAS Number
1165-39-5
Molecular Formula
C17H12O7
Formula Weight
328.3
Purity
≥98%
Formulation
A solid
Solubility(Learn about Variance in Solubility)
DMF: SolubleDMSO: SolubleEthanol: SolubleMethanol: Soluble
SMILES
O=C1C2=C(CCOC2=O)C3=C(C([C@@](C=CO4)([H])[C@@]4([H])O5)=C5C=C3OC)O1
InChi Code
InChI=1S/C17H12O7/c1-20-9-6-10-12(8-3-5-22-17(8)23-10)14-11(9)7-2-4-21-15(18)13(7)16(19)24-14/h3,5-6,8,17H,2,4H2,1H3/t8-,17+/m0/s1
InChi Key
XWIYFDMXXLINPU-WNWIJWBNSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Aflatoxin G1 is a mycotoxin that has been found in A. terricola.1 In vivo, aflatoxin G1 is lethal to ducklings (LD50 = 1.18 mg/kg).2 It induces hepatocellular carcinoma tumor formation and lethality in rats when administered at doses of 1.4 and 3 mg/animal, respectively. Aflatoxin G1 also inhibits liver and kidney succinate dehydrogenase and fumarase, as well as kidney cytochrome oxidase, NADH oxidase, α-glycerophosphate dehydrogenase, isocitrate dehydrogenase, and malate dehydrogenase in rats.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Moubasher, A.H., el-Kady, I.A., and Shoriet, A. Toxigenic Aspergilli isolated from different sources in Egypt. Ann. Nutr. Aliment. 31(4-6), 607-615 (1977).

    2. Wogan, G.N., Edwards, G.S., and Newberne, P.M. Structure-activity relationships in toxicity and carcinogenicity of aflatoxins and analogs. Cancer Res. 31(12), 1936-1942 (1971).

    3. Bai, N.J., Pai, M.R., and Venkitasubramanian, T.A. Mitochondrial function in aflatoxin toxicity. Indian J. Biochem. Biophys. 14(4), 347-349 (1977).