An Analytical Reference Material
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  • This product is qualified as a Reference Material that has been manufactured and tested to meet ISO/IEC 17025 and ISO 17034 international standards
  • This product is intended to be used as an analytical reference standard
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O-Desmethyl-cis-tramadol (hydrochloride)

Item No. 13976

Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • ODMT
  • O-Desmethyltramadol
Technical Information
Formal Name
rel-3-[(1R,2R)-2-[(dimethylamino)methyl]-1-hydroxycyclohexyl]-phenol, monohydrochloride
CAS Number
185453-02-5
Molecular Formula
C15H23NO2 • HCl
Formula Weight
285.8
Purity
≥98%
Formulation
A neat solid
SMILES
O[C@]1(C2=CC(O)=CC=C2)CCCC[C@@H]1CN(C)C.Cl
InChi Code
InChI=1S/C15H23NO2.ClH/c1-16(2)11-13-6-3-4-9-15(13,18)12-7-5-8-14(17)10-12;/h5,7-8,10,13,17-18H,3-4,6,9,11H2,1-2H3;1H/t13-,15+;/m1./s1
InChi Key
IRGWVAWLHXDKIX-PBCQUBLHSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    O-Desmethyl-cis-tramadol (hydrochloride) (Item No. 13976) is an analytical reference material categorized as an opioid.1,2 O-Desmethyl-cis-tramadol is an active metabolite of cis-tramadol (Item Nos. ISO60149 | 15919).1,2,3 It induces conditioned place preference in mice.2 This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Volz, M.R., and Moosmann, B. Development of a non-radioactive mass spectrometry-based binding assay at the μ-opioid receptor and its application for the determination of the binding affinities of 17 opiates/opioids as well as of the designer opioid isotonitazene and five further 2-benzylbenzimidazoles. Anal. Chim. Acta 1219, 339978 (2022).

    2. Nakamura, A., Narita, M., Miyoshi, K., et al. Changes in the rewarding effects induced by tramadol and its active metabolite M1 after sciatic nerve injury in mice. Psychopharmacology (Berl) 200(3), 307-316 (2008).

    3. Wu, W.N., McKown, L.A., Gauthier, A.D., et al. Metabolism of the analgesic drug, tramadol hydrochloride, in rat and dog. Xenobiotica 31(7), 423-441 (2001).