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  • This product is qualified as a Certified Reference Material (CRM) that has been manufactured and tested to meet ISO/IEC 17025 and ISO 17034 international standards
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O-Desmethyl-cis-tramadol-d6 (hydrochloride) (CRM)

A 1 mg/ml solution in methanol

Item No. 20593

Restricted Product (Schedule I)
Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • O-Desmethyltramadol-d6
  • ODMT-d6
Technical Information
Formal Name
rel-3-[(1R,2R)-2-[(dimethyl-d3 amino)methyl]-1-hydroxycyclohexyl]-phenol, monohydrochloride
CAS Number
1261393-87-6
Molecular Formula
C15H17D6NO2 • HCl
Formula Weight
291.8
Formulation
A 1 mg/ml solution in methanol
SMILES
O[C@]1(C2=CC=CC(O)=C2)CCCC[C@@H]1CN(C([2H])([2H])[2H])C([2H])([2H])[2H].Cl
InChi Code
InChI=1S/C15H23NO2.ClH/c1-16(2)11-13-6-3-4-9-15(13,18)12-7-5-8-14(17)10-12;/h5,7-8,10,13,17-18H,3-4,6,9,11H2,1-2H3;1H/t13-,15+;/m1./s1/i1D3,2D3;
InChi Key
IRGWVAWLHXDKIX-YATKDSQESA-N
Regulatory Information
DEA Schedule
I
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    1 mg

    $662

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    Product Description

    O-Desmethyl-cis-tramadol-d6 (hydrochloride) (CRM) (Item No. 20593) is intended for use as an internal standard for the quantification of O-desmethyl-cis-tramadol (Item Nos. 18751 | 13976) by GC- or LC-MS. O-Desmethyl-cis-tramadol is categorized as an opioid.12 It is an active metabolite of cis-tramadol (Item Nos. ISO60149 | 15919).3,1,2 O-Desmethyl-cis-tramadol induces conditioned place preference in mice.2 O-Desmethyl-cis-tramadol-d6 is regulated as a Schedule I compound in the United States. This product is intended for forensic and research applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Volz, M.R., and Moosmann, B. Development of a non-radioactive mass spectrometry-based binding assay at the μ-opioid receptor and its application for the determination of the binding affinities of 17 opiates/opioids as well as of the designer opioid isotonitazene and five further 2-benzylbenzimidazoles. Anal. Chim. Acta 1219, 339978 (2022).

    2. Nakamura, A., Narita, M., Miyoshi, K., et al. Changes in the rewarding effects induced by tramadol and its active metabolite M1 after sciatic nerve injury in mice. Psychopharmacology (Berl) 200(3), 307-316 (2008).

    3. Wu, W.N., McKown, L.A., Gauthier, A.D., et al. Metabolism of the analgesic drug, tramadol hydrochloride, in rat and dog. Xenobiotica 31(7), 423-441 (2001).