An inhibitor of α-glucosidases
Related Products
Labeled Version(s)
30139Miglitol-d4
Technical Support & Resources

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

Miglitol

Item No. 15014

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
1-(2-hydroxyethyl)-2R-(hydroxymethyl)-3R,4R,5S-piperidinetriol
CAS Number
72432-03-2
Synonyms
  • BAY-1099
  • Diastabol
  • Glyset
  • Seibule
Molecular Formula
C8H17NO5
Formula Weight
207.2
Purity
≥95%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMSO: 3 mg/mlPBS (pH 7.2): 10 mg/ml
SMILES
O[C@H]1[C@H](O)[C@@H](O)CN(CCO)[C@@H]1CO
InChi Code
InChI=1S/C8H17NO5/c10-2-1-9-3-6(12)8(14)7(13)5(9)4-11/h5-8,10-14H,1-4H2/t5-,6+,7-,8-/m1/s1
InChi Key
IBAQFPQHRJAVAV-ULAWRXDQSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    10 mg

    $90

    Add

    25 mg

    $154

    Add

    50 mg

    $197

    Add

    100 mg

    $349

    Add
    Cayman Chemical
    Explore Obesity & Metabolic Disease Resources

    Discover high-quality research tools to investigate GLP-1 mechanisms and next-generation metabolic targets.

    OBESITY RESEARCH SOLUTIONS
    Product Description

    Miglitol is an inhibitor of α-glucosidases (IC50s = 0.35, 0.11, 1.3, and 1.2 μM for human lysosomal α-glucosidase and rat sucrase, maltase, and isomaltase, respectively).1 It is selective for human α- over β-glucosidase (IC50 = 84 μM). Miglitol (10 mg/kg) decreases blood glucose levels in sucrose-loaded Goto-Kakizaki (GK) type 2 diabetic rats.2 Dietary administration of miglitol (40 mg/100 g diet) for 8 weeks decreases changes in HbA1c levels compared with control rats fed a normal diet. Formulations containing miglitol have been used in the treatment of type 2 diabetes.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Kuriyama, C., Kamiyama, O., Ikeda, K., et al. In vitro inhibition of glycogen-degrading enzymes and glycosidases by six-membered sugar mimics and their evaluation in cell cultures. Bioorg. Med. Chem. 16(15), 7330-7336 (2008).

    2. Goda, T., Suruga, K., Komori, A., et al. Effects of miglitol, an α-glucosidase inhibitor, on glycaemic status and histopathological changes in islets in non-obese, non-insulin-dependent diabetic Goto-Kakizaki rats. Br. J. Nutr. 98(4), 702-710 (2007).