An Analytical Reference Material
Features
  • This product is qualified as a Reference Material that has been manufactured and tested to meet ISO/IEC 17025 and ISO 17034 international standards
  • This product is intended to be used as an analytical reference standard
  • Bulk material is available for qualified institutions; please contact our sales department for pricing
Technical Support & Resources

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

α-hydroxy Alprazolam

Item No. 15287

Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • U-40125
Technical Information
Formal Name
8-chloro-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine-1-methanol
CAS Number
37115-43-8
Molecular Formula
C17H13ClN4O
Formula Weight
324.8
Purity
≥98%
Formulation (Request formulation change)
A neat solid
SMILES
OCC1=NN=C(N1C2=CC=C(Cl)C=C23)CN=C3C4=CC=CC=C4
InChi Code
InChI=1S/C17H13ClN4O/c18-12-6-7-14-13(8-12)17(11-4-2-1-3-5-11)19-9-15-20-21-16(10-23)22(14)15/h1-8,23H,9-10H2
InChi Key
ZURUZYHEEMDQBU-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    1 mg

    $90

    Add

    5 mg

    $391

    Add
    Cayman Chemical
    Forensic Lab Guide Wall Posters

    Discover our collection of drug identification, naming, and metabolism posters for your lab. We offer all of our posters at no cost to help support the forensic community.

    REQUEST YOURS
    Product Description

    α-hydroxy Alprazolam (Item No. 15287) is an analytical reference material categorized as a benzodiazepine.1,2 α-hydroxy Alprazolam is a major active metabolite of alprazolam (Item Nos. ISO60185 | 14255) that has a higher urinary recovery than 4-hydroxy alprazolam (Item No. 15878), another major metabolite.1 It is also a metabolite of adinazolam (Item Nos. 30186 | 18205).3 α-hydroxy Alprazolam has anticonvulsant activity in mice.2 This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Greenblatt, D.J., and Wright, C.E. Clinical pharmacokinetics of alprazolam. Therapeutic implications. Clin. Pharmacokinet. 24(6), 453-471 (1993).

    2. Hester, J.B., Jr., and Von Voigtlander, P. 6-Aryl-4H-s-triazolo[4,3-α][1,4]benzodiazepines. Influence of 1-substitution on pharmacological activity. J. Med. Chem. 22(11), 1390-1398 (1979).

    3. Fraser, A.D., Isner, A.F., and Bryan, W. Urinary screening for adinazolam and its major metabolites by the Emit d.a.u. and FPIA benzodiazepine assays with confirmation by HPLC. J. Anal. Toxicol. 17(7), 427-431 (1993).