A non-depolarizing muscle relaxant
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Vecuronium (bromide)

Item No. 15603

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
1-[(2β,3α,5α,16β,17β)-3,17-bis(acetyloxy)-2-(1-piperidinyl)androstan-16-yl]-1-methyl-piperidinium, monobromide
CAS Number
50700-72-6
Synonyms
  • NC 45
Molecular Formula
C34H57N2O4 • Br
Formula Weight
637.7
Purity
≥98%
Formulation
A solid
Solubility(Learn about Variance in Solubility)
DMF: 5 mg/mlDMSO: 5 mg/mlEthanol: 10 mg/mlPBS (pH 7.2): 1 mg/ml
SMILES
C[C@@]12[C@](C[C@H]([N+]3(C)CCCCC3)[C@@H]2OC(C)=O)([H])[C@]4([H])CC[C@@]5([H])C[C@H](OC(C)=O)[C@@H](N6CCCCC6)C[C@]5(C)[C@@]4([H])CC1.[Br-]
InChi Code
InChI=1S/C34H57N2O4.BrH/c1-23(37)39-31-20-25-12-13-26-27(34(25,4)22-29(31)35-16-8-6-9-17-35)14-15-33(3)28(26)21-30(32(33)40-24(2)38)36(5)18-10-7-11-19-36;/h25-32H,6-22H2,1-5H3;1H/q+1;/p-1/t25-,26+,27-,28-,29-,30-,31-,32-,33-,34-;/m0./s1
InChi Key
VEPSYABRBFXYIB-PWXDFCLTSA-M
Shipping & Storage Information
Storage
Room temperature
Shipping
Room temperature in continental US; may vary elsewhere
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    10 mg

    $68

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    50 mg

    $130

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    250 mg

    $547

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    Product Description

    Vecuronium is a non-depolarizing muscle relaxant derived from the aminosteroid pancuronium (Item No. 23778) and used adjunctively to general anesthesia.1 It competitively blocks cholinergic receptors at the motor end plate of the neuromuscular junction, inducing temporary paralysis.2 In humans, it has been shown to reduce muscle twitch tension with an ED50 value of 0.15 mg/kg for a duration of 27 minutes without inducing cardiovascular effects.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Fahey, M.R., Morris, R.B., Miller, R.D., et al. Clinical pharmacology of ORG NC45 (Norcuron™): A new nondepolarizing muscle relaxant. Anesthesiology 55(1), 6-11 (1981).

    2. Raghavendra, T. Neuromuscular blocking drugs: Discovery and development. J. R. Soc. Med. 95(7), 363-367 (2002).