An Analytical Reference Standard
Features
  • This product has been formulated as an exempt preparation which meets criteria established by the US DEA
  • Possession of a DEA Controlled Substance registration is not necessary nor is a DEA 222 form required to purchase this product
  • This product is intended to be used as an analytical reference standard
  • Bulk material is available for academic research at qualified institutions; please contact our sales department for pricing
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JWH 081 (exempt preparation)

Item No. 15665

Exempt Product (US)
Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(4-methoxy-1-naphthalenyl)(1-pentyl-1H-indol-3-yl)-methanone
CAS Number
210179-46-7
Molecular Formula
C25H25NO2
Formula Weight
371.5
Purity
≥98%
Formulation
A 1 mg/ml solution in methanol
λmax
213, 318 nm
SMILES
O=C(C1=CN(CCCCC)C2=C1C=CC=C2)C3=CC=C(OC)C4=CC=CC=C43
InChi Code
InChI=1S/C25H25NO2/c1-3-4-9-16-26-17-22(19-11-7-8-13-23(19)26)25(27)21-14-15-24(28-2)20-12-6-5-10-18(20)21/h5-8,10-15,17H,3-4,9,16H2,1-2H3
InChi Key
UBMPKJKGUQDHRM-UHFFFAOYSA-N
Regulatory Information
DEA Exempt Notification
This product is a DEA exempt preparation of a scheduled compound - does not require DEA Controlled Substance registration or DEA 222 form. For alternate sizes please contact sales.
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

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    Product Description

    JWH 081 (exempt preparation) (Item No. 15665) is an analytical reference standard categorized a synthetic cannabinoid.1,2 JWH 081 has been found in Spice/K2-type herbal blends and may have neurotoxic properties.3 JWH 081 is regulated as a Schedule I compound in the United States. JWH 081 (exempt preparation) (Item No. 15665) is provided as a DEA exempt preparation. This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Aung, M.M., Griffin, G., Huffman, J.W., et al. Influence of the N-1 alkyl chain length of cannabimimetic indoles upon CB1 and CB2 receptor binding. Drug Alcohol Depend. 60(2), 133-140 (2000).

    2. Huffman, J.W., Zengin, G., Wu, M.J., et al. Structure-activity relationships for 1-alkyl-3-(1-naphthoyl)indoles at the cannabinoid CB1 and CB2 receptors: Steric and electronic effects of naphthoyl substituents. New highly selective CB2 receptor agonists. Bioorg. Med. Chem. 13(1), 89-112 (2005).

    3. Cha, H.J., Seong, Y.H., Song, M.J., et al. Neurotoxicity of synthetic cannabinoids JWH-081 and JWH-210. Biomol. Ther. (Seoul) 23(6), 597-603 (2015).