Progesterone (CAS 57-83-0) | Cayman Chemical
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Progesterone

Item № 15876
CAS № 57-83-0
Purity ≥98%
product image
                (CAS 57-83-0)
SIZE PRICE QUANTITY SUBTOTAL
CART TOTAL
     1 g $15.00 0.00
     5 g $35.00 0.00

Pricing updated 2018-11-16. Prices are subject to change without notice.

Description
Synonyms
  • Crinone®
  • Cyclogest
  • Endometrin®
  • NSC 9704
  • NSC 64377
  • Utrogestan®

Progesterone, along with pregnenolone, is the biosynthetic precursor of all other steroid hormones. Progesterone is synthesized from cholesterol by the sequential action of desmolase in the mitochondria, which produces pregnenolone, followed by Δ4,5-isomerase in the outer mitochondrial membrane and smooth endoplasmic reticulum of steroid-secreting cells.1 Progesterone activates the human progesterone receptor with an EC50 value of 0.5 nM.2

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Technical Information
Formal Name
pregn-4-ene-3,20-dione
CAS Number
57-83-0
Synonyms
  • Crinone®
  • Cyclogest
  • Endometrin®
  • NSC 9704
  • NSC 64377
  • Utrogestan®
Molecular Formula
C21H30O2
Formula Weight
314.5
Purity
≥98%
Formulation
A crystalline solid
λmax
239 nm
SMILES
C[C@@]12[C@](CC[C@@H]2C(C)=O)([H])[C@]3([H])CCC4=CC(CC[C@]4(C)[C@@]3([H])CC1)=O
InChI Code
InChI=1S/C21H30O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12,16-19H,4-11H2,1-3H3/t16-,17+,18-,19-,20-,21+/m0/s1
InChI Key
RJKFOVLPORLFTN-LEKSSAKUSA-N

Warning - this product is not for human or veterinary use.

Shipping & Storage
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Stability
≥ 2 years
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Additional Information

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References & Product Citations
Product Description References

1. Erickson, G.F. The ovary: Basic principles and concepts. A. Physiology Endocrinology and Metabolism 3rd ed., 973-1015 (1995).

2. Pedram, B., van Oeveren, A., Mais, D.E., et al. A tissue-selective nonsteroidal progesterone receptor modulator: 7,9-Difluoro-5-(3-methylcyclohex-2-enyl)-2,2,4-trimethyl-1,2-dihydrochromeno[3,4-f]quinoline J. Med. Chem. 51(13), 3696-3699 (2008).

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