A “clickable” analog of CPTH2
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CAY10685

Item No. 16086

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
cyclopentanone, 2-[4-(4-chlorophenyl)-2-thiazolyl]-2-(2-propyn-1-yl)hydrazone
CAS Number
1613116-16-7
Synonyms
  • Click TagTM CAY10685
Molecular Formula
C17H16ClN3S
Formula Weight
329.8
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 10 mg/mlDMF:PBS(pH7.2) (1:2): 0.3 mg/mlDMSO: 5 mg/mlEthanol: 3 mg/ml
λmax
249 nm
SMILES
ClC1=CC=C(C2=CSC(N(CC#C)/N=C3CCCC\3)=N2)C=C1
InChi Code
InChI=1S/C17H16ClN3S/c1-2-11-21(20-15-5-3-4-6-15)17-19-16(12-22-17)13-7-9-14(18)10-8-13/h1,7-10,12H,3-6,11H2
InChi Key
JDLMHEOHMFFSDW-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    1 mg

    $36

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    5 mg

    $153

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    10 mg

    $268

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    25 mg

    $587

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    Cayman Chemical
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    Product Description

    CAY10685 is a cell-active analog of the lysine acetyltransferase inhibitor CPTH2 (Item No. 12086) that contains an alkyne moiety for use in click chemistry reactions.1 Its ability to inhibit N-acetyltransferase 10 activity has been used to modulate chromatin organization in order to study changes in nuclear architecture associated with cancer and certain laminopathies.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Larrieu, D., Britton, S., Demir, M., et al. Chemical inhibition of NAT10 corrects defects of laminopathic cells. Science 344(6183), 527-532 (2014).