The 9β-hydroxy stereoisomer of PGF2α
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Prostaglandin F2β

Item No. 16410

Technical Information
Formal Name
9β,11α,15S-trihydroxy-prosta-5Z,13E-dien-1-oic acid
CAS Number
4510-16-1
Synonyms
  • 9β-PGF2α
  • PGF2β
Molecular Formula
C20H34O5
Formula Weight
Purity
≥99%
A crystalline solid
10 mM Na2CO3: >6.5 mg/mlDMF: >100 mg/mlDMSO: >100 mg/mlEthanol: >100 mg/mlPBS (pH 7.2): >10 mg/ml
SMILES
O[C@H]1[C@H](C/C=C\CCCC(O)=O)[C@@H](/C=C/[C@@H](O)CCCCC)[C@H](O)C1
InChi Code
InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-19,21-23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,18+,19+/m0/s1
InChi Key
PXGPLTODNUVGFL-JZFBHDEDSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Prostaglandin F2β (PGF2β) is the 9β-hydroxy stereoisomer of PGF2α. It is much less active than PGF2α in antifertility and bronchoconstrictor activities.1,2,3 PGF2β exhibits bronchodilating activity in guinea pigs and cats and antagonizes the bronchoconstrictor activity of PGF2α.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Miller, W.L., and Sutton, M.J. Relative biological activity of certain prostaglandins and their enantiomers. Prostaglandins 11(1), 77-84 (1976).

    2. Gardiner, P.J., and Collier, H.O.J. Specific receptors for prostaglandins in airways. Prostaglandins 19(6), 819-841 (1980).

    3. Rosenthale, M.E., Dervinis, A., Kassarich, J., et al. Bronchodilating properties of the prostaglandin F2β in the guinea pig and cat. Prostaglandins 3(6), 767-772 (1973).