An insect repellent
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Labeled Version(s)
34424Picaridin-d3
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Picaridin

Item No. 16458

Technical Information
Formal Name
2-(2-hydroxyethyl)-1-piperidinecarboxylic acid, 1-methylpropyl ester
CAS Number
119515-38-7
Synonyms
  • Icaridin
  • KBR 3023
Molecular Formula
C12H23NO3
Formula Weight
Purity
≥95%
Formulation
A neat oil
DMF: 30 mg/mlDMSO: 25 mg/mlEthanol: 30 mg/mlPBS (pH 7.2): 2 mg/ml
SMILES
O=C(OC(C)CC)N1C(CCO)CCCC1
InChi Code
InChI=1S/C12H23NO3/c1-3-10(2)16-12(15)13-8-5-4-6-11(13)7-9-14/h10-11,14H,3-9H2,1-2H3
InChi Key
QLHULAHOXSSASE-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Picaridin is an insect repellent.1,2,3 It inhibits A. aegypti odorant receptor 2 (AaOR2) or AaOR8 in the presence of their odorant activators, indole and octenol, respectively, expressed in Xenopus oocytes (IC50s = 1,452 and 1,911 µM, respectively).1 Picaridin reduces the number of entries into a food chamber by female D. melanogaster in an olfactory-based choice assay.2 It acts synergistically with the non-pyrethroid insecticide pyrimiphos methyl to increase mortality of A. gambiae and reduce blood feeding when used at a concentration of 10 g/m2 on nets surrounding guinea pig cages.3 Formulations containing picaridin have been used as insect repellents against flies, mosquitoes, chiggers, ticks, and fleas.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Bohbot, J.D., and Dickens, J.C. Insect repellents: Modulators of mosquito odorant receptor activity. PLoS One 5(8), 1-11 (2010).

    2. Syed, Z., Pelletier, J., Flounders, E., et alGeneric insect repellent detector from the fruit fly Drosophila melanogaster. PLoS One 6(3), e17705 (2011).

    3. Pennetier, C., Corbel, V., Boko, P., et alSynergy between repellents and non-pyrethroid insecticides strongly extends the efficacy of treated nets against Anopheles gambiae. Malar. J. 6, 38 (2007).