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ENVIRONMENTAL TOXICOLOGY TOOLS & SERVICESPicaridin is an insect repellent.1,2,3 It inhibits A. aegypti odorant receptor 2 (AaOR2) or AaOR8 in the presence of their odorant activators, indole and octenol, respectively, expressed in Xenopus oocytes (IC50s = 1,452 and 1,911 µM, respectively).1 Picaridin reduces the number of entries into a food chamber by female D. melanogaster in an olfactory-based choice assay.2 It acts synergistically with the non-pyrethroid insecticide pyrimiphos methyl to increase mortality of A. gambiae and reduce blood feeding when used at a concentration of 10 g/m2 on nets surrounding guinea pig cages.3 Formulations containing picaridin have been used as insect repellents against flies, mosquitoes, chiggers, ticks, and fleas.
WARNING This product is not for human or veterinary use.
1. Insect repellents: Modulators of mosquito odorant receptor activity. PLoS One 5(8), 1-11 (2010).
2. Generic insect repellent detector from the fruit fly Drosophila melanogaster. PLoS One 6(3), e17705 (2011).
3. Synergy between repellents and non-