An internal standard for the quantification of picaridin
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Unlabeled Version(s)
16458Picaridin
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Picaridin-d3

Item No. 34424

Technical Information
Formal Name
2-(2-hydroxyethyl)-1-piperidinecarboxylic acid, 1-methyl-d3-propyl ester
CAS Number
2928067-33-6
Synonyms
  • Icaridin-d3
Molecular Formula
C12H20D3NO3
Formula Weight
Purity
≥99% deuterated forms (d1-d3)
Formulation
An oil
Chloroform: slightly solubleMethanol: slightly soluble
SMILES
O=C(N1C(CCO)CCCC1)OC(C([2H])([2H])[2H])CC
InChi Code
InChI=1S/C12H23NO3/c1-3-10(2)16-12(15)13-8-5-4-6-11(13)7-9-14/h10-11,14H,3-9H2,1-2H3/i2D3
InChi Key
QLHULAHOXSSASE-BMSJAHLVSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Picaridin-d3 is intended for use as an internal standard for the quantification of picaridin (Item No. 16458) by GC- or LC-MS. Picaridin is an insect repellant.1,2,3 It inhibits A. aegypti odorant receptor 2 (AaOR2) or AaOR8 in the presence of their odorant activators, indole and octenol, respectively, expressed in Xenopus oocytes (IC50s = 1,452 and 1,911 µM, respectively).1 Picaridin reduces the number of entries into a food chamber by female D. melanogaster in an olfactory-based choice assay.2 It acts synergistically with the non-pyrethroid insecticide pyrimiphos methyl to increase mortality of A. gambiae and reduce blood feeding when used at a concentration of 10 g/m2 on nets surrounding guinea pig cages.3 Formulations containing picaridin have been used as insect repellants against flies, mosquitoes, chiggers, ticks, and fleas.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Bohbot, J.D., and Dickens, J.C. Insect repellents: Modulators of mosquito odorant receptor activity. PLoS One 5(8), 1-11 (2010).

    2. Syed, Z., Pelletier, J., Flounders, E., et alGeneric insect repellent detector from the fruit fly Drosophila melanogaster. PLoS One 6(3), e17705 (2011).

    3. Pennetier, C., Corbel, V., Boko, P., et alSynergy between repellents and non-pyrethroid insecticides strongly extends the efficacy of treated nets against Anopheles gambiae. Malar. J. 6, 38 (2007).