A lysophospholipid
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1-Linoleoyl-2-hydroxy-sn-glycero-3-PC

Item No. 17153

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(7R,18Z,21Z)-4,7-dihydroxy-N,N,N-trimethyl-10-oxo-3,5,9-trioxa-4-phosphaheptacosa-18,21-dien-1-aminium, 4-oxide, inner salt
CAS Number
22252-07-9
Synonyms
  • LGPC
  • 1-Linoleoyl-2-hydroxy-sn-glycero-3-Phosphocholine
  • 1-Linoleoyl-2-hydroxy-sn-glycero-3-Phosphatidylcholine
  • PC(18:2/0:0)
  • 18:2/0:0-PC
Molecular Formula
C26H50NO7P
Formula Weight
519.7
Purity
≥95%
Formulation (Request formulation change)
A 5 mg/ml solution in chloroform
Solubility(Learn about Variance in Solubility)
PBS (pH 7.2): 2 mg/ml
SMILES
O[C@@H](COP(OCC[N+](C)(C)C)([O-])=O)COC(CCCCCCC/C=C\C/C=C\CCCCC)=O
InChi Code
InChI=1S/C26H50NO7P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-26(29)32-23-25(28)24-34-35(30,31)33-22-21-27(2,3)4/h9-10,12-13,25,28H,5-8,11,14-24H2,1-4H3/b10-9-,13-12-/t25-/m1/s1
InChi Key
SPJFYYJXNPEZDW-FTJOPAKQSA-N
Side Chain Carbon Sum
18:2
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    500 µg

    $129

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    5 mg

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    Product Description

    1-Linoleoyl-2-hydroxy-sn-glycero-3-PC (LGPC) is a lysophospholipid containing linoleic acid (Item Nos. 90150 | 90150.1 | 21909) at the sn-1 position that has been found in mouse heart, lung, liver, spleen, kidney, plasma, and serum.1 Serum levels of LGPC decrease with increasing insulin resistance and dysglycemia in humans.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Okudaira, M., Inoue, A., Shuto, A., et al. Separation and quantification of 2-acyl-1-lysophospholipids and 1-acyl-2-lysophospholipids in biological samples by LC-MS/MS. J. Lipid Res. 55(10), 2178-2192 (2014).

    2. Gall, W.E., Beebe, K., Lawton, K.A., et al. α-Hydroxybutyrate is an early biomarker of insulin resistance and glucose intolerance in a nondiabetic population. PLoS One 5(5), e10883 (2010).