An essential ω-6 PUFA
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Linoleic Acid (sodium salt)

Item No. 21909

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
9Z,12Z-octadecadienoic acid, monosodium salt
CAS Number
822-17-3
Synonyms
  • C18:2(9Z,12Z)
  • C18:2 n-6
  • FA 18:2
  • 9,12-Octadecadienoic Acid
  • Telfairic Acid
Molecular Formula
C18H31O2 • Na
Formula Weight
302.4
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
Ethanol: 1.5 mg/mlEthanol:PBS (pH 7.2) (1:1): 0.5 mg/ml
SMILES
CCCCC/C=C\C/C=C\CCCCCCCC([O-])=O.[Na+]
InChi Code
InChI=1S/C18H32O2.Na/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20;/h6-7,9-10H,2-5,8,11-17H2,1H3,(H,19,20);/q;+1/p-1/b7-6-,10-9-;
InChi Key
WYPBVHPKMJYUEO-NBTZWHCOSA-M
Side Chain Carbon Sum
18:2
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    100 mg

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    Product Description

    Linoleic acid is an essential ω-6 polyunsaturated fatty acid (PUFA).1 It is the most abundant PUFA in a variety of foods, and dietary sources of linoleic acid include vegetable oils, meats, nuts, seeds, and eggs. Linoleic acid (30 μM) increases migration of IEC-6 rat intestinal epithelial cells in a wound healing assay.2 Rats fed a linoleate-deficient diet exhibit decreased body weight and an increased ratio of eicosatrienoate to arachidonate in liver and serum phospholipids compared with rats fed a control diet, as well as mild scaling of forepaw skin.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Whelan, J., and Fritsche, K. Linoleic acid. Adv. Nutr. 4(3), 311-312 (2013).

    2. Ruthig, D.J., and Meckling-Gill, K.A. Both (n-3) and (n-6) fatty acids stimulate wound healing in the rat intestinal epithelial cell line, IEC-6. J. Nutr. 129(10), 1791-1798 (1999).

    3. Cunnane, S.C., and Anderson, M.J. Pure linoleate deficiency in the rat: Influence on growth, accumulation of n-6 polyunsaturates, and [1-14C]linoleate oxidation. J. Lipid Res. 38(4), 805-812 (1997).