An Analytical Reference Material
Features
  • This product is qualified as a Reference Material that has been manufactured and tested to meet ISO/IEC 17025 and ISO 17034 international standards
  • This product is intended to be used as an analytical reference standard
  • Bulk material is available for qualified institutions; please contact our sales department for pricing
Related Products
Alternative(s)
40658Lorazepam-d4 18728Lorazepam-d4 (CRM)
Certified Reference Material(s)
18731Lorazepam-13C2-d4 (CRM)
Unlabeled Version(s)
15891Lorazepam
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Lorazepam-13C2-d4

Item No. 17965

Restricted Product (Schedule IV)
Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
7-chloro-5-(2-chlorophenyl-d4)-3-hydroxy-1,3-dihydro-2H-benzo[e][1,4]diazepin-2-one-2,3-13C2
CAS Number
2747915-04-2
Molecular Formula
C13[13C]2H6D4Cl2N2O2
Formula Weight
327.2
Purity
≥98%
Formulation
A neat solid
SMILES
ClC1=C([2H])C([2H])=C([2H])C([2H])=C1C(C(C=C(Cl)C=C2)=C2N3)=N[13CH](O)[13C]3=O
InChi Code
InChI=1S/C15H10Cl2N2O2/c16-8-5-6-12-10(7-8)13(19-15(21)14(20)18-12)9-3-1-2-4-11(9)17/h1-7,15,21H,(H,18,20)/i1D,2D,3D,4D,14+1,15+1
InChi Key
DIWRORZWFLOCLC-FCIHXEGWSA-N
Regulatory Information
DEA Schedule
IV
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Lorazepam-13C2-d4 (Item No. 17965) is an analytical reference material intended for use as an internal standard for the quantification of lorazepam (Item Nos. ISO60202 | 15891) by GC- or LC-MS. Lorazepam is categorized as a benzodiazepine that has anxiolytic properties.1,2 It is a metabolite of diclazepam (Item Nos. 28623 | 15554).2 Formulations containing lorazepam have been used in the treatment of anxiety. Lorazepam-13C2-d4 is regulated as a Schedule IV compound in the United States. This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Baldwin, D., Woods, R., Lawson, R., et al. Efficacy of drug treatments for generalised anxiety disorder: Systematic review and meta-analysis. BMJ 342, d1199 (2011).

    2. Moosmann, B., Bisel, P., and Auwärter, V. Characterization of the designer benzodiazepine diclazepam and preliminary data on its metabolism and pharmacokinetics. Drug Test Anal. 6(7-8), 757-763 (2014).