An intermediate in purine metabolism
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

Product Categories

Product Type

Biochemicals

Research Area

Xanthosine 5'-monophosphate (sodium salt)

Item No. 18134

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
5'-xanthylic acid, disodium salt
CAS Number
25899-70-1
Synonyms
  • XMP
Molecular Formula
C10H11N4O9P • 2Na
Formula Weight
408.2
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
PBS (pH 7.2): 10 mg/ml
λmax
250 nm
SMILES
O[C@H]1[C@@H](O)[C@H](N2C=NC(C(N3)=O)=C2NC3=O)O[C@@H]1COP([O-])([O-])=O.[Na+].[Na+]
InChi Code
InChI=1S/C10H13N4O9P.2Na/c15-5-3(1-22-24(19,20)21)23-9(6(5)16)14-2-11-4-7(14)12-10(18)13-8(4)17;;/h2-3,5-6,9,15-16H,1H2,(H2,19,20,21)(H2,12,13,17,18);;/q;2*+1/p-2/t3-,5-,6-,9-;;/m1../s1
InChi Key
QQPVYRBCIRHGSZ-LGVAUZIVSA-L
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    10 mg

    $36

    Add

    50 mg

    $153

    Add

    100 mg

    $268

    Add

    500 mg

    $920

    Add
    Product Description

    Xanthosine 5'-monophosphate (XMP) is an intermediate in purine metabolism, the product of the rate limiting step in the generation of guanosine monophosphate, which is important for DNA, RNA, and glycoprotein synthesis. XMP is generated from inosine-5’-monophosphate (IMP; Item No. 18135) by IMP dehydrogenase (IMPDH). Inhibitors of IMPDH, including ribavirin (Item No. 16757) and mycophenolate mofetil (Item No. 13988), have potential applications as antiviral and anti-cancer drugs.1,2,3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Watkins, W.J., Chen, J.M., Cho, A., et al. Phosphonic acid-containing analogues of mycophenolic acid as inhibitors of IMPDH. Bioorg. Med. Chem. Lett. 16(13), 3479-3483 (2006).

    2. Naik, G.S., and Tyagi, M.G. A pharmacological profile of ribavirin and monitoring of its plasma concentration in chronic hepatitis C infection. J. Clin. Exp. Hepatol. 2(1), 42-54 (2012).

    3. Borden, K.L.B., and Culjkovic-Kraljacic, B. Ribavirin as an anti-cancer therapy: acute myeloid leukemia and beyond? Leuk. Lymphoma 51(10), 1805-1815 (2010).