A carbamate pesticide
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Active Metabolite(s)
24210Aldicarb sulfone
Labeled Version(s)
39580Aldicarb-d3
Metabolite(s)
24211Aldicarb Sulfoxide
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Aldicarb

Item No. 18466

Technical Information
Formal Name
O-[(methylamino)carbonyl]oxime-2-methyl-2-(methylthio)-propanal
CAS Number
116-06-3
Synonyms
  • NSC 379586
  • 2-methyl-2-(methylthio)-Propionaldehyde
  • UC21149
Molecular Formula
C7H14N2O2S
Formula Weight
Purity
≥98%
Formulation
A crystalline solid
DMSO: Slightly solubleMethanol: Slightly soluble
λmax
248 nm
SMILES
CNC(O/N=C/C(C)(C)SC)=O
InChi Code
InChI=1S/C7H14N2O2S/c1-7(2,12-4)5-9-11-6(10)8-3/h5H,1-4H3,(H,8,10)/b9-5+
InChi Key
QGLZXHRNAYXIBU-WEVVVXLNSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Aldicarb is a carbamate pesticide.1 It is an acetylcholinesterase (AChE) inhibitor with an IC50 value of 5 µM.2 Aldicarb induces mortality in the two-spotted spider mite (T. urticae) with an LC50 value of 21 ppm in a slide-dip assay and in the nematode (M. exigua) with an LC50 value of 24 µg/l.3,4 It has been used to study CREB and acetylcholine signaling.5 Formulations containing aldicarb have been used as pesticides in agriculture.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Baron, R.L. A carbamate insecticide: A case study of aldicarb. Environ. Health Perspect. 102 (Suppl. 11), 23-27 (1994).

    2. Smulders, C.J., Bueters, T.J., Van Kleef, R.G., et alSelective effects of carbamate pesticides on rat neuronal nicotinic acetylcholine receptors and rat brain acetylcholinesterase. Toxicol. Appl. Pharmacol. 193(2), 139-146 (2003).

    3. Knowles, C.O., Errampalli, D.D., and E-Sayed, G.N. Comparative toxicities of selected pesticides to bulb mite (Acari: Acaridae) and twospotted spider mite (Acari: Tetranychidae). J. Econ. Entomol. 81(6), 1586-1591 (1988).

    4. Nunes, A.d.S. Organic substances for nematode control in coffee plants. Master's, 36 (2008).

    5. Suo, S., and Ishiura, S. Dopamine modulates acetylcholine release via octopamine and CREB signaling in Caenorhabditis elegans. PLoS One 8(8), e72578 (2013).