An internal standard for the quantification of aldicarb
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Unlabeled Version(s)
18466Aldicarb
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Aldicarb-d3

Item No. 39580

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-methyl-2-(methylthio)propanal O-((methyl-d3)carbamoyl) oxime
CAS Number
1795142-83-4
Molecular Formula
C7H11D3N2O2S
Formula Weight
193.3
Purity
≥99% deuterated forms (d1-d3)
Formulation
A solid
Solubility(Learn about Variance in Solubility)
Water: Soluble
SMILES
[2H]C([2H])([2H])NC(ON=CC(C)(C)SC)=O
InChi Code
InChI=1S/C7H14N2O2S/c1-7(2,12-4)5-9-11-6(10)8-3/h5H,1-4H3,(H,8,10)/i3D3
InChi Key
QGLZXHRNAYXIBU-HPRDVNIFSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    1 mg

    $219

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    Product Description

    Aldicarb-d3 is intended for use as an internal standard for the quantification of aldicarb (Item No. 18466) by GC- or LC-MS. Aldicarb is a carbamate pesticide.1 It is an acetylcholinesterase (AChE) inhibitor with an IC50 value of 5 µM.2 Aldicarb induces mortality in the two-spotted spider mite (T. urticae) with an LC50 value of 21 ppm in a slide-dip assay and in the nematode (M. exigua) with an LC50 value of 24 µg/L.3,4 It has been used to study CREB and acetylcholine signaling.5 Formulations containing aldicarb have been used as pesticides in agriculture.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Baron, R.L. A carbamate insecticide: A case study of aldicarb. Environ. Health Perspect. 102 (Suppl. 11), 23-27 (1994).

    2. Smulders, C.J., Bueters, T.J., Van Kleef, R.G., et al. Selective effects of carbamate pesticides on rat neuronal nicotinic acetylcholine receptors and rat brain acetylcholinesterase. Toxicol. Appl. Pharmacol. 193(2), 139-146 (2003).

    3. Knowles, C.O., Errampalli, D.D., and E-Sayed, G.N. Comparative toxicities of selected pesticides to bulb mite (Acari: Acaridae) and twospotted spider mite (Acari: Tetranychidae). J. Econ. Entomol. 81(6), 1586-1591 (1988).

    4. Nunes, A.d.S. Organic substances for nematode control in coffee plants. Master's, 36 (2008).

    5. Suo, S., and Ishiura, S. Dopamine modulates acetylcholine release via octopamine and CREB signaling in Caenorhabditis elegans. PLoS One 8(8), e72578 (2013).