A pyrimidine nucleoside
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Labeled Version(s)
36317Uridine-d2
Pro-drug Form(s)
274452',3',5'-Triacetyluridine
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Uridine

Item No. 20300

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
CAS Number
58-96-8
Synonyms
  • NSC 20256
  • 1-β-D-Ribofuranosyluracil
  • Uracil-1-β-D-ribofuranoside
  • β-Uridine
Molecular Formula
C9H12N2O6
Formula Weight
244.2
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 16 mg/mlDMSO: 10 mg/mlPBS (pH 7.2): 5 mg/ml
λmax
261 nm
SMILES
O=C(NC(C=C1)=O)N1[C@H]2[C@H](O)[C@H](O)[C@@H](CO)O2
InChi Code
InChI=1S/C9H12N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)/t4-,6-,7-,8-/m1/s1
InChi Key
DRTQHJPVMGBUCF-XVFCMESISA-N
Shipping & Storage Information
Storage
Room temperature
Shipping
Room temperature in continental US; may vary elsewhere
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    5 g

    $36

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    10 g

    $63

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    25 g

    $103

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    50 g

    $196

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    Product Description

    Uridine is a pyrimidine nucleoside composed of uracil (Item No. 26088) and ribose.1 It forms complementary base pairs with adenosine (Item No. 21232) in RNA.2 Uridine can be catabolized to uracil via uridine phosphorylase, and it can be phosphorylated to UMP (Item No. 35382) by uridine-cytidine kinase (UCK).1,3 It is replaced with thymidine (Item No. 20519) in DNA.4

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Yamamoto, T., Koyama, H., Kurajoh, M., et al. Biochemistry of uridine in plasma. Clin. Chim. Acta 412(19-20), 1712-1724 (2011).

    2. Zinshteyn, B., and Nishikura, K. Adenosine-to-inosine RNA editing. Wiley Interdiscip. Rev. Syst. Biol. Med. 1(2), 202-209 (2009).

    3. Van Rompay, A.R., Norda, A., Lindén, K., et al. Phosphorylation of uridine and cytidine nucleoside analogs by two human uridine-cytidine kinases. Mol. Pharmacol. 59(5), 1181-1186 (2001).

    4. Knoop, V. When you can't trust the DNA: RNA editing changes transcript sequences. Cell. Mol. Life Sci. 68(4), 567-586 (2011).