A mycotoxin
Related Products
Isomer(s)
13227Fumonisin B2
Labeled Version(s)
31274Fumonisin B3-13C34
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Fumonisin B3

Item No. 20434

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(2R,2'R)-1,1'-[(1S,2R)-1-[(2S,4R,11S,12S)-12-amino-4,11-dihydroxy-2-methyltridecyl]-2-[(1R)-1-methylpentyl]-1,2-ethanediyl]ester, 1,2,3-propanetricarboxylic acid
CAS Number
1422359-85-0
Synonyms
  • FB3
Molecular Formula
C34H59NO14
Formula Weight
705.8
Purity
≥98%
Formulation
A solid
SMILES
C[C@H](N)[C@@H](O)CCCCCC[C@@H](O)C[C@H](C)C[C@H](OC(C[C@H](C(O)=O)CC(O)=O)=O)[C@H](OC(C[C@H](C(O)=O)CC(O)=O)=O)[C@H](C)CCCC
InChi Code
InChI=1S/C34H59NO14/c1-5-6-11-21(3)32(49-31(43)19-24(34(46)47)17-29(40)41)27(48-30(42)18-23(33(44)45)16-28(38)39)15-20(2)14-25(36)12-9-7-8-10-13-26(37)22(4)35/h20-27,32,36-37H,5-19,35H2,1-4H3,(H,38,39)(H,40,41)(H,44,45)(H,46,47)/t20-,21+,22-,23+,24+,25+,26-,27-,32+/m0/s1
InChi Key
CPCRJSQNWHCGOP-STOIETHLSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $912

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    Product Description

    Fumonisin B3 (FB3) is a mycotoxin that has been found in Fusarium.1 It is cytotoxic to primary rat hepatocytes when used at concentrations of 125, 250, and 500 µM.2 Dietary administration of FB3 (0.05%) for 14 or 21 days induces hepatocyte nodules, a marker of cancer initiation, in rats. FB3 has been detected in corn and corn-based foods and livestock feeds.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Rheeder, J.P., Marasas, W.F.O., and Vismer, H.F. Production of fumonisin analogs by Fusarium species. Appl. Environ. Microbiol. 68(5), 2101-2105 (2002).

    2. Gelderblom, W.C.A., Cawood, M.E., Snyman, S.D., et al. Structure-activity relationships of fumonisins in short-term carcinogenesis and cytotoxicity assays. Food Chem. Toxicol. 31(6), 407-414 (1993).

    3. Bullerman, L.B. Occurrence of Fusarium and fumonisins on food grains and in foods. Fumonisins in food 27-38 (1996).