A neonicotinoid insecticide
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Labeled Version(s)
26783Nitenpyram-d3
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Nitenpyram

Item No. 21271

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(1E)-N-[(6-chloro-3-pyridinyl)methyl]-N-ethyl-N'-methyl-2-nitro-1,1-ethenediamine
CAS Number
150824-47-8
Synonyms
  • NTP
Molecular Formula
C11H15ClN4O2
Formula Weight
270.7
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMSO: Slightly solubleMethanol: Slightly soluble
λmax
213, 270, 343 nm
SMILES
ClC1=CC=C(CN(CC)/C(NC)=C/[N+]([O-])=O)C=N1
InChi Code
InChI=1S/C11H15ClN4O2/c1-3-15(11(13-2)8-16(17)18)7-9-4-5-10(12)14-6-9/h4-6,8,13H,3,7H2,1-2H3/b11-8+
InChi Key
CFRPSFYHXJZSBI-DHZHZOJOSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    50 mg

    $49

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    100 mg

    $86

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    Cayman Chemical
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    Product Description

    Nitenpyram is a neonicotinoid insecticide.1 It is an antagonist of housefly neuronal-type nicotinic acetylcholine receptors (nAChRs; IC50 = 2 nM for housefly head homogenates).2 Nitenpyram induces mortality in brown planthopper (N. lugens) larvae when used at a concentration of 0.5 ppm.3 Orally administered nitenpyram (11.4, 11.4, and 57 mg/animal, respectively) eliminates live adult fleas on cats, small dogs, and large dogs after six hours of treatment.4 It also reduces the number of aphids, ladybugs, ladybug larvae, lacewings, and syrphid larvae on adult cotton plants when applied to cotton seeds at a concentration of 4 g/kg of seeds.5 Formulations containing nitenpyram have been used in the control of fleas and ticks on companion animals.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Vo, D.T., Hsu, W.H., Abu-Basha, E.A., et al. Insect nicotinic acetylcholine receptor agonists as flea adulticides in small animals. J. Vet. Pharmacol. Ther. 33(4), 315-322 (2010).

    2. Nauen, R., Ebbinghaus, U., and Tietjen, K. Ligands of the nicotinic acetylcholine receptor as insecticides. Pest. Manag. Sci. 55(5), 608-610 (1999).

    3. Minamida, I., Iwanaga, K., Tabuchi, T., et al. Synthesis and insecticidal activity of acyclic nitroethene compounds containing a heteroarylmethylamino group. J. Pesticide Sci. 18, 41-48 (1993).

    4. Dobson, P., Tinembart, O., Fisch, R.D., et al. Efficacy of nitenpyram as a systemic flea adulticide in dogs and cats. Vet. Rec. 147(25), 709-713 (2000).

    5. Zhang, Z., Zhang, X., Wang, Y., et al. Nitenpyram, dinotefuran, and thiamethoxam used as seed treatments act as efficient controls against Aphis gossypii via high residues in cotton leaves. J. Agric. Food Chem. 64(49), 9276-9285 (2016).