A nematicide
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Fluensulfone

Item No. 21554

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
5-chloro-2-[(3,4,4-trifluoro-3-buten-1-yl)sulfonyl]-thiazole
CAS Number
318290-98-1
Molecular Formula
C7H5ClF3NO2S2
Formula Weight
291.7
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 30 mg/mlEthanol: 30 mg/ml
λmax
225, 271 nm
SMILES
ClC1=CN=C(S(CC/C(F)=C(F)\F)(=O)=O)S1
InChi Code
InChI=1S/C7H5ClF3NO2S2/c8-5-3-12-7(15-5)16(13,14)2-1-4(9)6(10)11/h3H,1-2H2
InChi Key
XSNMWAPKHUGZGQ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    1 mg

    $36

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    5 mg

    $153

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    10 mg

    $268

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    25 mg

    $587

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    Cayman Chemical
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    Product Description

    Fluensulfone is a fluoroalkenyl nematicide that inhibits mobility of P. penetrans, P. thornei, and X. index migratory nematodes when used at a concentration of 4 mg/L.1 It reduces the number of P. penetrans and P. thornei nematodes in soil when applied at a concentration of 2 mg/L before planting crops. Fluensulfone (1,200 mg/kg) is metabolized by the murine-specific cytochrome P450 (CYP) isoform Cyp2f2 in mouse lung club cells and induces species-specific bronchiolar hyperplasias in mice.2 Formulations containing fluensulfone have been used to control nematode populations in agriculture.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Oka, Y. Nematicidal activity of fluensulfone against some migratory nematodes under laboratory conditions. Pest Manag. Sci. 70(12), 1850-1858 (2014).

    2. Strupp, C., Banas, D.A., Cohen, S.M., et al. Relationship of metabolism and cell proliferation to the mode of action of fluensulfone-induced mouse lung tumors: Analysis of their human relevance using the IPCS framework. Toxicol. Sci. 128(1), 284-294 (2012).