A nucleotide sugar and P2Y14 receptor agonist
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UDP-β-D-Glucose (sodium salt)

Item No. 21620

Technical Information
Formal Name
uridine 5'-(trihydrogen pyrophosphate), mono-β-D-glucopyranosyl ester, disodium salt
CAS Number
7333-33-7
Molecular Formula
C15H22N2O17P2 • 2Na
Formula Weight
Purity
≥95%
A crystalline solid
PBS (pH 7.2): 10 mg/ml
λmax
261 nm
SMILES
O=P(OP(OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C=CC(NC2=O)=O)O1)([O-])=O)([O-])O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O.[Na+].[Na+]
InChi Code
InChI=1S/C15H24N2O17P2.2Na/c18-3-5-8(20)10(22)12(24)14(32-5)33-36(28,29)34-35(26,27)30-4-6-9(21)11(23)13(31-6)17-2-1-7(19)16-15(17)25;;/h1-2,5-6,8-14,18,20-24H,3-4H2,(H,26,27)(H,28,29)(H,16,19,25);;/q;2*+1/p-2/t5-,6-,8-,9-,10+,11-,12-,13-,14+;;/m1../
InChi Key
PKJQEQVCYGYYMM-BYFFMYLLSA-L
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    UDP-β-D-glucose is a nucleotide sugar, purinergic P2Y14 receptor agonist, and β-anomer of UDP-α-D-glucose (Item No. 15602).1 It induces inositol phosphate production in COS-7 cells expressing the human P2Y14 receptor (EC50 = 0.588 µM).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Ko, H., Das, A., Carter, R.L., et alMolecular recognition in the P2Y14 receptor: Probing the structurally permissive terminal sugar moiety of uridine-5'-diphosphoglucose. Bioorg. Med. Chem. 17(14), 5298-5311 (2009).