A nucleotide sugar
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

UDP-α-D-Galactose (sodium salt)

Item No. 34664

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
uridine 5′-(trihydrogen diphosphate), sodium salt, P′-α-D-galactopyranosyl ester
CAS Number
137868-52-1
Synonyms
  • UDP-Gal
  • Uridine-5'-diphosphate-α-D-Galactose
Molecular Formula
C15H22N2O17P2 • 2Na
Formula Weight
610.3
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
PBS (pH 7.2): 10 mg/ml
λmax
263 nm
SMILES
O[C@H]1[C@@](N2C(NC(C=C2)=O)=O)([H])O[C@@H]([C@H]1O)COP(OP(O[C@H]3O[C@@H]([C@@H]([C@@H]([C@H]3O)O)O)CO)([O-])=O)([O-])=O.[Na+].[Na+]
InChi Code
InChI=1S/C15H24N2O17P2.2Na/c18-3-5-8(20)10(22)12(24)14(32-5)33-36(28,29)34-35(26,27)30-4-6-9(21)11(23)13(31-6)17-2-1-7(19)16-15(17)25;;/h1-2,5-6,8-14,18,20-24H,3-4H2,(H,26,27)(H,28,29)(H,16,19,25);;/q;2*+1/p-2/t5-,6-,8+,9-,10+,11-,12-,13-,14-;;/m1../s1
InChi Key
PKJQEQVCYGYYMM-QKYKBPIOSA-L
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    5 mg

    $36

    Add

    10 mg

    $63

    Add

    25 mg

    $128

    Add

    50 mg

    $169

    Add
    Product Description

    UDP-α-D-galactose is an endogenous nucleotide sugar that is used by glycosyltransferases to transfer α-D-galactose residues to substrates.1 It is an agonist of the purinergic P2Y14 receptor (EC50 = 0.67 µM), an atypical P2Y receptor involved in the activation of dendritic and glial cells.2 Levels of UDP-α-D-galactose in red blood cells are decreased in patients with phenylketonuria (PKU) and maple syrup urine disease, inborn errors of amino acid metabolism characterized by mutations in the gene encoding phenylalanine hydroxylase (PAH) and a deficiency in the branched-chain α-keto acid dehydrogenase enzyme complex, respectively.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Hennet, T. The galactosyltransferase family. Cell Mol. Life Sci. 59(7), 1081-1095 (2002).

    2. Jacobson, K.A., Ivanov, A.A., de Castro, S., et al. Development of selective agonists and antagonists of P2Y receptors. Purinergic Signal. 5(1), 75-89 (2009).

    3. Gibson, J.B., Berry, G.T., Palmieri, M.J., et al. Sugar nucleotide concentrations in red blood cells of patients on protein- and lactose-limited diets: Effect of galactose supplementation. Am. J. Clin. Nutr. 63(5), 704-708 (1996).