A dietary fatty acid
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Palmitelaidic Acid

Item No. 9001798

Technical Information
Formal Name
(9E)-hexadecenoic acid
CAS Number
10030-73-6
Synonyms
  • C16:1(9E)
  • FA 16:1
  • 9-trans-Hexadecenoic Acid
Molecular Formula
C16H30O2
Formula Weight
Purity
≥98%
A 100 mg/ml solution in ethanol
DMF: 30 mg/mlDMSO: 30 mg/mlEthanol: >50 mg/ml
SMILES
CCCCCC/C=C/CCCCCCCC(O)=O
InChi Code
InChI=1S/C16H30O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16(17)18/h7-8H,2-6,9-15H2,1H3,(H,17,18)/b8-7+
InChi Key
SECPZKHBENQXJG-BQYQJAHWSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    Product Description

    Palmitelaidic acid is a trans isomer of palmitoleic acid (Item Nos. 10009871 | 21911) and dietary fatty acid that has been found in dairy fat products and various partially hydrogenated oils.1,2 It decreases nitric oxide (NO) production and levels of soluble E-selectin in isolated human aortic endothelial cells (HAECs) when used at a concentration of 20 µM.1 Palmitelaidic acid (49 µM) inhibits Sendai virus-induced hemolysis of isolated human erythrocytes.3 Increased serum levels of palmitelaidic acid are associated with higher levels of LDL, but lower levels of triglycerides, fasting insulin, blood pressure, and incidence of diabetes.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Livingstone, K.M., Givens, D.I., Jackson, K.G., et alComparative effect of dairy fatty acids on cell adhesion molecules, nitric oxide and relative gene expression in healthy and diabetic human aortic endothelial cells. Atherosclerosis 234(1), 65-72 (2014).

    2. Mozaffarian, D., de Oliveira Otto, M.C., Lemaitre, R.N., et altrans-Palmitoleic acid, other dairy fat biomarkers, and incident diabetes: The multi-ethnic study of atherosclerosis (MESA). Am. J. Clin. Nutr. 97(4), 854-861 (2013).

    3. MacDonald, R.C., Ore, V.D., and MacDonald, R.I. Inhibition of sendai virus-induced hemolysis by long chain fatty acids. Virology 134(1), 103-117 (1984).

    Product Citations

    Magtanong, L., Ko, P.-J., To, M., et alExogenous monounsaturated fatty acids promote a ferroptosis-resistant cell state. Cell Chem. Biol. 26(3), 420-432 (2019).