A proton pump inhibitor
Related Products
Metabolite(s)
22569Lansoprazole sulfone
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Product Categories

Product Type

Small Molecule Modulators
Small Molecule Inhibitors
ATPases

Research Area

(S)-Lansoprazole

Item No. 21967

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-[(S)-[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole
CAS Number
138530-95-7
Synonyms
  • (-)-Lansoprazole
Molecular Formula
C16H14F3N3O2S
Formula Weight
369.4
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 30 mg/mlDMSO:PBS (pH 7.2) (1:1): 0.5 mg/mlEthanol: 5 mg/ml
λmax
284 nm
SMILES
CC1=C(C[S@@](C2=NC(C=CC=C3)=C3N2)=O)N=CC=C1OCC(F)(F)F
InChi Code
InChI=1S/C16H14F3N3O2S/c1-10-13(20-7-6-14(10)24-9-16(17,18)19)8-25(23)15-21-11-4-2-3-5-12(11)22-15/h2-7H,8-9H2,1H3,(H,21,22)/t25-/m0/s1
InChi Key
MJIHNNLFOKEZEW-VWLOTQADSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    500 µg

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    1 mg

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    5 mg

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    10 mg

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    Product Description

    (S)-Lansoprazole is a proton pump inhibitor that irreversibly inhibits H+/K+-stimulated ATPase pumps in parietal cells (IC50 = 5.2 µM), inhibiting gastric acid secretion and increasing intragastric pH.1 It also inhibits acid formation in isolated canine parietal cells (IC50 = 82 µM). (S)-Lansoprazole is an enantiomerically pure form of lansoprazole (Item No. 13627). Both (S)- and (R)-lansoprazole (Item No. 18235) are pharmacologically active with similar potencies.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Schubert, M.L. Pharmacotherapy for acid/peptic disorders. Yale J. Biol. Med. 69(2), 197-201 (1996).