An antioxidant used in animal feed
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Metabolite(s)
29823Ethoxyquin Dimer
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Ethoxyquin

Item No. 23094

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
6-ethoxy-1,2-dihydro-2,2,4-trimethyl-quinoline
CAS Number
91-53-2
Synonyms
  • NSC 6795
Molecular Formula
C14H19NO
Formula Weight
217.3
Purity
≥98%
Formulation (Request formulation change)
A neat oil
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 30 mg/mlEthanol: 30 mg/mlEthanol:PBS (pH 7.2) (1:3): 0.25 mg/ml
λmax
229, 357 nm
SMILES
CCOC1=CC=C2C(C(C)=CC(C)(C)N2)=C1
InChi Code
InChI=1S/C14H19NO/c1-5-16-11-6-7-13-12(8-11)10(2)9-14(3,4)15-13/h6-9,15H,5H2,1-4H3
InChi Key
DECIPOUIJURFOJ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    100 mg

    $28

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    Product Description

    Ethoxyquin is an antioxidant that is widely used in animal feed to protect against lipid peroxidation and fat rancidity in chicken, salmon, and beef.1 In vitro, ethoxyquin protects human lymphocytes against hydrogen peroxide-induced DNA damage and reduces micronuclei formation.2 In vivo, it reduces the number of chromosome aberrations, micronuclei, and dominant lethal mutations induced by cyclophosphamide (Item No. 13849) in mice, rats, and Chinese hamsters.3,4 Ethoxyquin also induces chromosome aberrations such as atypical translocations, breaks, and dicentrics in human lymphocytes and CHO cells as well as in vivo kidney and bladder damage in rats.1 Dietary administration of ethoxyquin (50 and 150 mg/kg, w.w.) increases lipid composition in yellow croaker fish.5 Formulations containing ethoxyquin have been used as preservatives in animal feed and in the control of fungi in agriculture.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Blaszczyk, A., Augustyniak, A., and Skolimowski, J. Ethoxyquin: An antioxidant used in animal feed. Int. J. Food Sci. 2013, 585931 (2013).

    2. Blaszczyk, A., and Skolimowski, J. Comparative analysis of cytotoxic, genotoxic and antioxidant effects of 2,2,4,7-tetramethyl-1,2,3,4-tetrahydroquinoline and ethoxyquin on human lymphocytes. Chem. Biol. Interact. 162(1), 70-80 (2006).

    3. Renner, H.W. Antimutagenic effect of an antioxidant in mammals. Mutat. Res. 135(2), 125-129 (1984).

    4. Renner, H.W., and Knoll, M. Antimutagenic effects on male germ cells of mice. Mutat. Res. 140(2-3), 127-129 (1984).

    5. Wang, J., Ai, Q., Mai, K., et al. Effects of dietary ethoxyquin on growth performance and body composition of large yellow croaker Pseudosciaena crocea. Aquaculture 306(1-4), 80-84 (2010).