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Explore additional resources to study natural toxins, pollutants including PFAS and 6-PPD-Q, and their biological effects.
ENVIRONMENTAL TOXICOLOGY TOOLS & SERVICESAcetamiprid is a neonicotinoid insecticide that acts as an agonist of insect nicotinic acetylcholine receptors (nAChRs).1 It activates nAChRs containing N. lugens α1 and rat β2 subunits with an EC50 value of 67 µM in X. laevis oocytes. Acetamiprid administered to pregnant mice at a dose of 1 mg/kg leads to sexual and aggressive behaviors in adult male offspring while doses of 1 and 10 mg/kg decrease anxiety-like behavior of adult male offspring in the light-dark transition test.2 Formulations containing acetamiprid have been used to control sucking insects on crops and pets.
WARNING This product is not for human or veterinary use.
1. A nicotinic acetylcholine receptor mutation (Y151S) causes reduced agonist potency to a range of neonicotinoid insecticides. J. Neurochem. 99(4), 1273-1281 (2006).
2. In utero and lactational exposure to acetamiprid induces abnormalities in socio-