An isomer of linoleic acid
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9(Z),11(Z)-Conjugated Linoleic Acid

Item No. 24582

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
9Z,11Z-octadecadienoic acid
CAS Number
544-70-7
Synonyms
  • 9Z,11Z-CLA
  • FA 18:2
  • 9(Z),11(Z)-Octadecadienoic Acid
Molecular Formula
C18H32O2
Formula Weight
280.5
Purity
≥96%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Chloroform: SolubleEthanol: SolubleEther: SolubleMethanol: Soluble
SMILES
CCCCCC/C=C\C=C/CCCCCCCC(O)=O
InChi Code
InChI=1S/C18H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h7-10H,2-6,11-17H2,1H3,(H,19,20)/b8-7-,10-9-
InChi Key
JBYXPOFIGCOSSB-QRLRYFCNSA-N
Side Chain Carbon Sum
18:2
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    5 mg

    $85

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    10 mg

    $134

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    25 mg

    $208

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    Product Description

    9(Z),11(Z)-Conjugated linoleic acid is an isomer of linoleic acid (Item No. 90150) that has been found in milk from cows and other animals.1,2 It is cytotoxic to Caco-2 human colon cancer cells (EC50 = 446.1 µM) and induces changes in the miRNA profile, including an upregulation hsa-miR-146a-5p and downregulation of hsa-miR-32-5p, which is involved in apoptosis.3 [Matreya, LLC. Catalog No. 1248]

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Brainbridge, M.L., Egolf, E., Barlow, J.W., et al. Milk from cows grazing on cool-season pastures provides an enhanced profile of bioactive fatty acids compared to those grazed on a monoculture of pearl millet. Food Chem. 217, 750-755 (2017).

    2. Revilla, I., Escuredo, O., González-Martín, M.I., et al. Fatty acids and fat-soluble vitamins in ewe’s milk predicted by near infrared reflectance spectroscopy. Determination of seasonality. Food Chem. 214, 468-477 (2017).

    3. Köpke, S., Buhrke, T., and Lampen, A. miRNA expression in human intestinal Caco-2 cells is comparably regulated by cis- and trans-fatty acids. Lipids 50(3), 227-239 (2015).

    Product Citations

    Zhang, L.J., Salekeen, R., Soto-Palma, C., et al. Article polyunsaturated lipid senolytics exploit a ferroptotic vulnerability in senescent cells. Cell Press Blue 1(1), 100004 (2026).