An internal standard for the quantification of progesterone
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Unlabeled Version(s)
15876Progesterone
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Progesterone-d9

Item No. 25047

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
pregn-4-ene-3,20-dione-2,2,4,6,6,17,21,21,21-d9
CAS Number
15775-74-3
Synonyms
  • Cyclogest-d9
Molecular Formula
C21H21D9O2
Formula Weight
323.5
Purity
≥98%
Formulation
A solid
Solubility(Learn about Variance in Solubility)
Acetonitrile: 1 mg/mlEthanol: 1 mg/mlMethanol: 1 mg/ml
SMILES
C[C@@]12[C@](CC[C@]2([2H])C(C([2H])([2H])[2H])=O)([H])[C@]3([H])CC([2H])([2H])C4=C([2H])C(C([2H])([2H])C[C@]4(C)[C@@]3([H])CC1)=O
InChi Code
InChI=1S/C21H30O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12,16-19H,4-11H2,1-3H3/t16-,17+,18-,19-,20-,21+/m0/s1/i1D3,4D2,8D2,12D,17D
InChi Key
RJKFOVLPORLFTN-PQIPVKAESA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $189

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    Product Description

    Progesterone-d9 is intended for use as an internal standard for the quantification of progesterone (Item No. 15876) by GC- or LC-MS. Progesterone is the biosynthetic precursor of all other steroid hormones.1 Progesterone is synthesized from cholesterol by the sequential action of desmolase in the mitochondria, which produces pregnenolone, followed by Δ4,5-isomerase in the outer mitochondrial membrane and smooth endoplasmic reticulum of steroid-secreting cells. Progesterone activates the human progesterone receptor with an EC50 value of 0.5 nM.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Erickson, G.F. The ovary: Basic principles and concepts. A. Physiology. Endocrinology and Metabolism 973-1015 (1995).

    2. Pedram, B., van Oeveren, A., Mais, D.E., et al. A tissue-selective nonsteroidal progesterone receptor modulator: 7,9-Difluoro-5-(3-methylcyclohex-2-enyl)-2,2,4-trimethyl-1,2-dihydrochromeno[3,4-f]quinoline. J. Med. Chem. 51(13), 3696-3699 (2008).