A fungal metabolite
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Benzomalvin B

Item No. 25088

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(7E)-(+)-6,7-dihydro-6-methyl-7-(phenylmethylene)-quinazolino[3,2-a][1,4]benzodiazepine-5,13-dione
CAS Number
157047-97-7
Molecular Formula
C24H17N3O2
Formula Weight
379.4
Purity
≥95%
Formulation
A solid
SMILES
O=C1N2C(/C(N(C)C(C3=C2C=CC=C3)=O)=C/C4=CC=CC=C4)=NC5=CC=CC=C51
InChi Code
InChI=1S/C24H17N3O2/c1-26-21(15-16-9-3-2-4-10-16)22-25-19-13-7-5-11-17(19)24(29)27(22)20-14-8-6-12-18(20)23(26)28/h2-15H,1H3/b21-15-
InChi Key
HXDZMNFJQNZXKW-QNGOZBTKSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

    1 mg

    $208

    Add

    5 mg

    $779

    Add
    Product Description

    Benzomalvin B is a fungal metabolite originally isolated from Penicillium.1 It acts as an antagonist of neurokinin-1 (NK1) receptors, inhibiting binding of substance P (Item No. 24035) by 24% in vitro when used at a concentration of 100 μg/ml.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Sun, H.H., Barrow, C.J., Sedlock, D.M., et al. Benzomalvins, new substance P inhibitors from a Penicillium sp. J. Antibiot. (Tokyo) 47(5), 515-522 (1994).