A triacylglycerol
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1,2,3-Tridocosanoyl Glycerol

Item No. 26847

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
docosanoic acid, 1,2,3-propanetriyl ester
CAS Number
18641-57-1
Synonyms
  • Glycerol Tribehenate
  • Glycerol Tridocosanoate
  • TG(22:0/22:0/22:0)
  • Tribehenin
  • Tridocosanoin
  • Tridocosanoylglycerol
Molecular Formula
C69H134O6
Formula Weight
1059.8
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 10 mg/mL
SMILES
O=C(CCCCCCCCCCCCCCCCCCCCC)OCC(OC(CCCCCCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCCCCCC)=O
InChi Code
InChI=1S/C69H134O6/c1-4-7-10-13-16-19-22-25-28-31-34-37-40-43-46-49-52-55-58-61-67(70)73-64-66(75-69(72)63-60-57-54-51-48-45-42-39-36-33-30-27-24-21-18-15-12-9-6-3)65-74-68(71)62-59-56-53-50-47-44-41-38-35-32-29-26-23-20-17-14-11-8-5-2/h66H,4-65H2,1-3H3
InChi Key
DMBUODUULYCPAK-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    500 mg

    $69

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    1 g

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    Cayman Chemical
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    Product Description

    1,2,3-Tridocosanoyl glycerol is a triacylglycerol that contains docosanoic acid (Item No. 9000338) at the sn-1, sn-2, and sn-3 positions. Formulations containing 1,2,3-tridocosanoyl glycerol have been used to form the lipid matrices of nanostructured lipid carriers and solid lipid nanoparticles (SLNs).1,2,3 Formulations containing 1,2,3-tridocosanoyl glycerol have also been used in cosmetic products as thickening and skin-conditioning agents.4

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Aburahma, M.H., and Badr-Eldin, S.M. Compritol 888 ATO: A multifunctional lipid excipient in drug delivery systems and nanopharmaceuticals. Expert Opin. Drug Discov. 11(12), 1865-1883 (2014).

    2. Almeida, H., Lobão, P., Frigerio, C., et al. Preparation, characterization and biocompatibility studies of thermoresponsive eyedrops based on the combination of nanostructured lipid carriers (NLC) and the polymer Pluronic F-127 for controlled delivery of ibuprofen. Pharm. Dev. Technol. 22(3), 336-349 (2017).

    3. Wang, T., Xue, J., Hu, Q., et al. Preparation of lipid nanoparticles with high loading capacity and exceptional gastrointestinal stability for potential oral delivery applications. J. Colloid. Interface Sci. 507, 119-130 (2017).

    4. Johnson, W., Jr., and Panel, C.I.R.E. Final report on the safety assessment of trilaurin, triarachidin, tribehenin, tricaprin, tricaprylin, trierucin, triheptanoin, triheptylundecanoin, triisononanoin, triisopalmitin, triisostearin, trilinolein, trimyristin, trioctanoin, triolein, tripalmitin, tripalmitolein, triricinolein, tristearin, triundecanoin, glyceryl triacetyl hydroxystearate, glyceryl triacetyl ricinoleate, and glyceryl stearate diacetate. Int. J. Toxicol. 20(Suppl 4), 61-94 (2001).