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Palmitelaidic acid-d13 is intended for use as an internal standard for the quantification of palmitelaidic acid (Item No. 9001798) by GC- or LC-MS. Palmitelaidic acid is a trans isomer of palmitoleic acid (Item Nos. 10009871 | 21911) and dietary fatty acid that has been found in dairy fat products and various partially hydrogenated oils.1,2 It decreases nitric oxide (NO) production and levels of soluble E-selectin in isolated human aortic endothelial cells (HAECs) when used at a concentration of 20 µM.1 Palmitelaidic acid (49 µM) inhibits Sendai virus-induced hemolysis of isolated human erythrocytes.3 Increased serum levels of palmitelaidic acid are associated with higher levels of LDL, but lower levels of triglycerides, fasting insulin, blood pressure, and incidence of diabetes.2
WARNING This product is not for human or veterinary use.
1. Comparative effect of dairy fatty acids on cell adhesion molecules, nitric oxide and relative gene expression in healthy and diabetic human aortic endothelial cells. Atherosclerosis 234(1), 65-72 (2014).
2. trans-
3. Inhibition of sendai virus-