A flavonoid with antioxidant activity
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Naringin Dihydrochalcone

Item No. 27791

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
1-[4-[[2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-1-propanone
CAS Number
18916-17-1
Molecular Formula
C27H34O14
Formula Weight
582.6
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 30 mg/mlEthanol: 30 mg/ml
λmax
226, 284 nm
SMILES
OC1=C(C(CCC2=CC=C(O)C=C2)=O)C(O)=CC(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O[C@@]4([H])[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O4)=C1
InChi Code
InChI=1S/C27H34O14/c1-11-20(33)22(35)24(37)26(38-11)41-25-23(36)21(34)18(10-28)40-27(25)39-14-8-16(31)19(17(32)9-14)15(30)7-4-12-2-5-13(29)6-3-12/h2-3,5-6,8-9,11,18,20-29,31-37H,4,7,10H2,1H3/t11-,18+,20-,21+,22+,23-,24+,25+,26-,27+/m0/s1
InChi Key
CWBZAESOUBENAP-QVNVHUMTSA-N
Origin
Plant/Pomelo peel
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Certificates of Analysis & Batch Specific Data

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    5 g

    $95

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    10 g

    $168

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    25 g

    $370

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    50 g

    $554

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    Product Description

    Naringin dihydrochalcone is an artificial sweetener and flavonoid that has been isolated from various plants and has antioxidant activity.1,2 It scavenges ABTS (Item No. 27317), oxygen, and 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. 14805) radicals in cell free assays (IC50s = 24, 322.8, and 318.9 μM, respectively).2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Gentili, B., and Horowtiz, R.M. Chromatography of dihydrochalcone sweeteners and related compounds: A reagent for detecting dihydrochalcones. J. Chromatogr. 63(5730), 467-469 (1971).

    2. Li, X., Chen, B., Xie, H., et al. Antioxidant structure-activity relationship analysis of five dihydrochalcones. Molecules 23(5), E1162 (2018).