An acetate form of (±)-α-tocopherol
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(±)-α-Tocopherol Acetate

Item No. 28399

Technical Information
Formal Name
3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-ol, 6-acetate
CAS Number
7695-91-2
Synonyms
  • all-rac-α-Tocopherol Acetate
  • DL-α-Tocopherol Acetate
  • DL-Vitamin E acetate
Molecular Formula
C31H52O3
Formula Weight
Purity
≥95%
A liquid
DMF: solubleDMSO: solubleEthanol: solubleEthanol:PBS (pH 7.2) (1:1): 0.5 mg/ml
SMILES
CC1=C2C(CCC(CCCC(C)CCCC(C)CCCC(C)C)(C)O2)=C(C)C(OC(C)=O)=C1C
InChi Code
InChI=1S/C31H52O3/c1-21(2)13-10-14-22(3)15-11-16-23(4)17-12-19-31(9)20-18-28-26(7)29(33-27(8)32)24(5)25(6)30(28)34-31/h21-23H,10-20H2,1-9H3
InChi Key
ZAKOWWREFLAJOT-UHFFFAOYSA-N
Origin
Synthetic
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    (±)-α-Tocopherol acetate is an acetate form of (±)-α-tocopherol (Item No. 25985).1 It inhibits heat-stress-induced decreases in blastocyst number in pregnant mice and glutathione (GSH) levels in isolated mouse zygotes in a model of hyperthermia-induced pre-implantation embryonic death when administered at a dose of 1 g/kg. Dietary administration of (±)-α-tocopherol acetate (1,050 IU/kg) prevents sidestream cigarette smoke-induced decreases in body weight and lung dynamic compliance and increases in lung resistance in mice. It also increases IL-1β, IL-4, and IFN-γ levels in bronchoalveolar lavage fluid (BALF) in the same model.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Sakamoto, N., Ozawa, M., Yokotani-Tomita, K., et alDL-α-Tocopherol acetate mitigates maternal hyperthermia-induced pre-implantation embryonic death accompanied by a reduction of physiological oxidative stress in mice. Reproduction 135(4), 489-496 (2008).