An internal standard for the quantification of amodiaquine
Related Products
Unlabeled Version(s)
15954Amodiaquine
Technical Support & Resources

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

Amodiaquine-d10

Item No. 28525

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-((bis(ethyl-d5)amino)methyl)-4-((7-chloroquinolin-4-yl)amino)phenol
CAS Number
1189449-70-4
Synonyms
  • Camoquine-d10
  • Flavoquine-d10
Molecular Formula
C20H12ClD10N3O
Formula Weight
365.9
Purity
≥99% deuterated forms (d1-d10)
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Chloroform: solubleMethanol: soluble
SMILES
OC(C=C1)=C(CN(C([2H])([2H])C([2H])([2H])[2H])C([2H])([2H])C([2H])([2H])[2H])C=C1NC2=CC=NC3=C2C=CC(Cl)=C3
InChi Code
InChI=1S/C20H22ClN3O/c1-3-24(4-2)13-14-11-16(6-8-20(14)25)23-18-9-10-22-19-12-15(21)5-7-17(18)19/h5-12,25H,3-4,13H2,1-2H3,(H,22,23)/i1D3,2D3,3D2,4D2
InChi Key
OVCDSSHSILBFBN-MWUKXHIBSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    1 mg

    $303

    Add
    Cayman Chemical
    Neutrophil Biology Wall Poster

    Explore how neutrophils shape the immune response in health and disease. This poster highlights neutrophil pathogen defense mechanisms, including phagocytosis, degranulation, and NETosis, as well as neutrophil roles in inflammation and NET-associated pathologies.

    DOWNLOAD NOW
    Product Description

    Amodiaquine-d10 is intended for use as an internal standard for the quantification of amodiaquine (Item No. 15954) by GC- or LC-MS. Amodiaquine is a prodrug form of the antimalarial compound N-desethyl amodiaquine (Item No. 20822).1,2 It is active against several strains of P. falciparum in vitro (EC50s = 0.23-0.52 nM) and exhibits a synergistic effect when used in combination with N-desethyl amodiaquine.1 Amodiaquine dose-dependently inhibits development of parasitemia in a mouse model of P. berghei infection.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Mariga, S.T., Gil, J.P., Sisowath, C., et al. Synergism between amodiaquine and its major metabolite, desethylamodiaquine, against Plasmodium falciparum in vitro. Antimicrob. Agents Chemother. 48(11), 4089-4096 (2004).

    2. Sá, J.M., Chong, J.L., and Wellems, T.E. Malaria drug resistance: New observations and developments. Essays Biochem. 51, 137-160 (2014).

    3. Jacobs, R.L., Alling, D.W., and Cantrell, W.F. An evaluation of antimalarial combinations against Plasmodium berghei in the mouse. J. Parasitol. 49(6), 920-925 (1963).